[HTML][HTML] Hydrophilic polymers: Current trends and visions for the future

N Bayliss, BVKJ Schmidt - Progress in Polymer Science, 2023 - Elsevier
Hydrophilic polymers are a major class of polymers in polymer science. They are found in
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …

Coacervate droplets for synthetic cells

Z Lin, T Beneyton, JC Baret, N Martin - Small Methods, 2023 - Wiley Online Library
The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …

Stress granules plug and stabilize damaged endolysosomal membranes

C Bussi, A Mangiarotti, C Vanhille-Campos, B Aylan… - Nature, 2023 - nature.com
Endomembrane damage represents a form of stress that is detrimental for eukaryotic cells,.
To cope with this threat, cells possess mechanisms that repair the damage and restore …

Biomolecular condensates modulate membrane lipid packing and hydration

A Mangiarotti, M Siri, NW Tam, Z Zhao… - Nature …, 2023 - nature.com
Membrane wetting by biomolecular condensates recently emerged as a key phenomenon in
cell biology, playing an important role in a diverse range of processes across different …

Autophagy preferentially degrades non-fibrillar polyQ aggregates

DY Zhao, FJB Bäuerlein, I Saha, FU Hartl… - Molecular Cell, 2024 - cell.com
Aggregation of proteins containing expanded polyglutamine (polyQ) repeats is the
cytopathologic hallmark of a group of dominantly inherited neurodegenerative diseases …

Biomolecular condensates in contact with membranes

A Mangiarotti, R Dimova - Annual Review of Biophysics, 2024 - annualreviews.org
Biomolecular condensates are highly versatile membraneless organelles involved in a
plethora of cellular processes. Recent years have witnessed growing evidence of the …

Actin polymerization counteracts prewetting of N-WASP on supported lipid bilayers

T Wiegand, J Liu, L Vogeley, I LuValle-Burke… - Proceedings of the …, 2024 - pnas.org
Cortical condensates, transient punctate-like structures rich in actin and the actin nucleation
pathway member Neural Wiskott-Aldrich syndrome protein (N-WASP), form during activation …

[HTML][HTML] Biomolecular condensates as drivers of membrane trafficking and remodelling

R Ravindran, SW Michnick - Current Opinion in Cell Biology, 2024 - Elsevier
Membrane remodelling is essential for the trafficking of macromolecules throughout the cell,
a process that regulates various aspects of cellular health and pathology. Recent studies …

Interfacial energy-mediated bulk transport across artificial cell membranes

JQ Tian, MY Chang, C Chen, ZH Luo… - Nature Chemical …, 2024 - nature.com
The construction of synthetic cells that exhibit some of the complex behaviors of biological
cells is a fundamental challenge. A major bottleneck is the transport of substances across …

Interfacing coacervates with membranes: from artificial organelles and hybrid protocells to intracellular delivery

T Lu, S Javed, C Bonfio, E Spruijt - Small methods, 2023 - Wiley Online Library
Compartmentalization is crucial for the functioning of cells. Membranes enclose and protect
the cell, regulate the transport of molecules entering and exiting the cell, and organize …