BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Several genes are implicated in spermatogenesis and fertility regulation, and these genes
are presently being analysed in clinical practice due to their involvement in male factor …

Despite continuous expansion of the RNA binding protein (RBP) world, there is a lack of
systematic understanding of RBPs in the mammalian testis, which harbors one of the most …

Placental DNA methylation (DNAm) may be a potential mechanism underlying the effects of
prenatal bisphenol analogues (BPs) exposure on reproductive health. Based on the …

Infertility is a global health problem affecting one in six couples, with 50% of cases attributed
to male infertility. Spermatozoa are male gametes, specialized cells that can be divided into …

STUDY QUESTION What are the genetic causes of total fertilization failure (TFF) in a
proband suffering from male infertility? SUMMARY ANSWER Novel compound …

The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus;
however, the physiological roles of the PT in sperm are largely uncertain. Here, we reveal …

The perinuclear theca (PT) is a cytoskeletal element encapsulating the sperm nucleus;
however, our understanding of the physiological roles of PT in sperm is very limited. We …

Background Livestock populations are under constant selective pressure for higher
productivity levels for different selective purposes. This pressure results in the selection of …

This brief report concerns the role of human sperm morphology assessment in different
fields of male infertility: basic research, genetics, assisted reproduction technologies …