Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

Polyphenolic materials are a class of fascinating and versatile bioinspired materials for
biointerfacial engineering. In particular, due to the presence of active chemical groups, a …

Immunogenic cell death (ICD)-associated immunogenicity can be evoked through reactive
oxygen species (ROS) produced via endoplasmic reticulum (ER) stress. In this study, we …

Although nanocatalytic medicine has demonstrated its advantages in tumor therapy, the
outcomes heavily relie on substrate concentration and the metabolic pathways are still …

Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

Calcium overload, characterized by an abnormal cytoplasm accumulation of free calcium
ions (Ca 2+), is a widely recognized cause of damage in numerous cell types and even of …

Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Metabolic viability based high throughput assays like MTT and MTS are widely used in
assessing the cell viability. However, alteration in both mitochondrial content and …