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A unifying perspective on neural manifolds and circuits for cognition
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
behaviour. One approach seeks to identify neural circuit elements that carry out specific …
Attractor and integrator networks in the brain
In this Review, we describe the singular success of attractor neural network models in
describing how the brain maintains persistent activity states for working memory, corrects …
describing how the brain maintains persistent activity states for working memory, corrects …
Building an allocentric travelling direction signal via vector computation
Many behavioural tasks require the manipulation of mathematical vectors, but, outside of
computational models,,,,,–, it is not known how brains perform vector operations. Here we …
computational models,,,,,–, it is not known how brains perform vector operations. Here we …
[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
The connectome of the adult Drosophila mushroom body provides insights into function
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
[HTML][HTML] Network statistics of the whole-brain connectome of Drosophila
A Lin, R Yang, S Dorkenwald, A Matsliah, AR Sterling… - Nature, 2024 - nature.com
Brains comprise complex networks of neurons and connections, similar to the nodes and
edges of artificial networks. Network analysis applied to the wiring diagrams of brains can …
edges of artificial networks. Network analysis applied to the wiring diagrams of brains can …
Rethinking retrosplenial cortex: Perspectives and predictions
The last decade has produced exciting new ideas about retrosplenial cortex (RSC) and its
role in integrating diverse inputs. Here, we review the diversity in forms of spatial and …
role in integrating diverse inputs. Here, we review the diversity in forms of spatial and …
Dopamine promotes head direction plasticity during orienting movements
In neural networks that store information in their connection weights, there is a tradeoff
between sensitivity and stability,. Connections must be plastic to incorporate new …
between sensitivity and stability,. Connections must be plastic to incorporate new …
Converting an allocentric goal into an egocentric steering signal
Neuronal signals that are relevant for spatial navigation have been described in many
species,,,,,,,,–. However, a circuit-level understanding of how such signals interact to guide …
species,,,,,,,,–. However, a circuit-level understanding of how such signals interact to guide …
Neural dynamics and architecture of the heading direction circuit in zebrafish
Animals generate neural representations of their heading direction. Notably, in insects,
heading direction is topographically represented by the activity of neurons in the central …
heading direction is topographically represented by the activity of neurons in the central …