A unifying perspective on neural manifolds and circuits for cognition

C Langdon, M Genkin, TA Engel - Nature Reviews Neuroscience, 2023 - nature.com
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …

Attractor and integrator networks in the brain

M Khona, IR Fiete - Nature Reviews Neuroscience, 2022 - nature.com
In this Review, we describe the singular success of attractor neural network models in
describing how the brain maintains persistent activity states for working memory, corrects …

Building an allocentric travelling direction signal via vector computation

C Lyu, LF Abbott, G Maimon - Nature, 2022 - nature.com
Many behavioural tasks require the manipulation of mathematical vectors, but, outside of
computational models,,,,,–, it is not known how brains perform vector operations. Here we …

[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

BK Hulse, H Haberkern, R Franconville… - Elife, 2021 - elifesciences.org
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

The connectome of the adult Drosophila mushroom body provides insights into function

F Li, JW Lindsey, EC Marin, N Otto, M Dreher… - Elife, 2020 - elifesciences.org
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

[HTML][HTML] Network statistics of the whole-brain connectome of Drosophila

A Lin, R Yang, S Dorkenwald, A Matsliah, AR Sterling… - Nature, 2024 - nature.com
Brains comprise complex networks of neurons and connections, similar to the nodes and
edges of artificial networks. Network analysis applied to the wiring diagrams of brains can …

Rethinking retrosplenial cortex: Perspectives and predictions

AS Alexander, R Place, MJ Starrett, ER Chrastil… - Neuron, 2023 - cell.com
The last decade has produced exciting new ideas about retrosplenial cortex (RSC) and its
role in integrating diverse inputs. Here, we review the diversity in forms of spatial and …

Dopamine promotes head direction plasticity during orienting movements

YE Fisher, M Marquis, I D'Alessandro, RI Wilson - Nature, 2022 - nature.com
In neural networks that store information in their connection weights, there is a tradeoff
between sensitivity and stability,. Connections must be plastic to incorporate new …

Converting an allocentric goal into an egocentric steering signal

P Mussells Pires, L Zhang, V Parache, LF Abbott… - Nature, 2024 - nature.com
Neuronal signals that are relevant for spatial navigation have been described in many
species,,,,,,,,–. However, a circuit-level understanding of how such signals interact to guide …

Neural dynamics and architecture of the heading direction circuit in zebrafish

L Petrucco, H Lavian, YK Wu, F Svara, V Štih… - Nature …, 2023 - nature.com
Animals generate neural representations of their heading direction. Notably, in insects,
heading direction is topographically represented by the activity of neurons in the central …