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[HTML][HTML] Stimuli-responsive synthetic helical polymers
M Lago-Silva, M Fernández-Míguez… - Chemical Society …, 2024 - pubs.rsc.org
Synthetic dynamic helical polymers (supramolecular and covalent) and foldamers share the
helix as a structural motif. Although the materials are different, these systems also share …
helix as a structural motif. Although the materials are different, these systems also share …
Peptidomimetic toolbox for drug discovery
The art of transforming peptides into drug leads is still a dynamic and fertile field in medicinal
chemistry and drug discovery. Peptidomimetics can respond to peptide limitations by …
chemistry and drug discovery. Peptidomimetics can respond to peptide limitations by …
Supramolecular helical systems: helical assemblies of small molecules, foldamers, and polymers with chiral amplification and their functions
In this review, we describe the recent advances in supramolecular helical assemblies
formed from chiral and achiral small molecules, oligomers (foldamers), and helical and …
formed from chiral and achiral small molecules, oligomers (foldamers), and helical and …
Urea derivatives in modern drug discovery and medicinal chemistry
The urea functionality is inherent to numerous bioactive compounds, including a variety of
clinically approved therapies. Urea containing compounds are increasingly used in …
clinically approved therapies. Urea containing compounds are increasingly used in …
Peptide hydrogen-bonded organic frameworks
Hydrogen-bonded porous frameworks (HPFs) are versatile porous crystalline frameworks
with diverse applications. However, designing chiral assemblies or biocompatible materials …
with diverse applications. However, designing chiral assemblies or biocompatible materials …
[HTML][HTML] Artificial molecular machines
The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …
rewards could come from bridging the gap between synthetic molecular systems and the …
From precision polymers to complex materials and systems
Complex chemical systems, such as living biological matter, are highly organized structures
based on discrete molecules in constant dynamic interactions. These natural materials can …
based on discrete molecules in constant dynamic interactions. These natural materials can …
Self-assembly of emulsion droplets through programmable folding
In the realm of particle self-assembly, it is possible to reliably construct nearly arbitrary
structures if all the pieces are distinct,–, but systems with fewer flavours of building blocks …
structures if all the pieces are distinct,–, but systems with fewer flavours of building blocks …
Structure‐based design of inhibitors of protein–protein interactions: mimicking peptide binding epitopes
M Pelay‐Gimeno, A Glas, O Koch… - Angewandte Chemie …, 2015 - Wiley Online Library
Protein–protein interactions (PPIs) are involved at all levels of cellular organization, thus
making the development of PPI inhibitors extremely valuable. The identification of selective …
making the development of PPI inhibitors extremely valuable. The identification of selective …
Sequence-controlled polymers
Background During the last few decades, progress has been made in manipulating the
architecture of synthetic polymer materials. However, the primary structure—that is, the …
architecture of synthetic polymer materials. However, the primary structure—that is, the …