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Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
New insight into circRNAs: characterization, strategies, and biomedical applications
XY Feng, SX Zhu, KJ Pu, HJ Huang, YQ Chen… - … hematology & oncology, 2023 - Springer
Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
[HTML][HTML] Circular RNAs in cancer
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skip** events of thousands of genes in …
formed by precursor mRNA back-splicing or skip** events of thousands of genes in …
A 360 view of circular RNAs: From biogenesis to functions
JE Wilusz - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
The first circular RNA (circRNA) was identified more than 40 years ago, but it was only
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
recently appreciated that circRNAs are common outputs of many eukaryotic protein‐coding …
A comprehensive overview and evaluation of circular RNA detection tools
Circular RNA (circRNA) is mainly generated by the splice donor of a downstream exon
joining to an upstream splice acceptor, a phenomenon known as backsplicing. It has been …
joining to an upstream splice acceptor, a phenomenon known as backsplicing. It has been …
A circular RNA promotes tumorigenesis by inducing c-myc nuclear translocation
Circular RNAs (circRNAs) are a subclass of noncoding RNAs widely expressed in
mammalian cells. We report here the tumorigenic capacity of a circRNA derived from …
mammalian cells. We report here the tumorigenic capacity of a circRNA derived from …
Lessons from non-canonical splicing
Recent improvements in experimental and computational techniques that are used to study
the transcriptome have enabled an unprecedented view of RNA processing, revealing many …
the transcriptome have enabled an unprecedented view of RNA processing, revealing many …
Circular RNA: an emerging key player in RNA world
Insights into the circular RNA (circRNA) exploration have revealed that they are abundant in
eukaryotic transcriptomes. Diverse genomic regions can generate different types of RNA …
eukaryotic transcriptomes. Diverse genomic regions can generate different types of RNA …
Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective
Circular RNAs (circRNAs) are a subclass of non-coding RNAs that lack free 3′ and 5′
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …