Innovations in genomic antimicrobial resistance surveillance

NE Wheeler, V Price, E Cunningham-Oakes… - The Lancet …, 2023 - thelancet.com
Whole-genome sequencing of antimicrobial-resistant pathogens is increasingly being used
for antimicrobial resistance (AMR) surveillance, particularly in high-income countries …

Exploiting genomics for antimicrobial resistance surveillance at One Health interfaces

DM Muloi, E Jauneikaite, MF Anjum, SY Essack… - The Lancet …, 2023 - thelancet.com
The intersection of human, animal, and ecosystem health at One Health interfaces is
recognised as being of key importance in the evolution and spread of antimicrobial …

Building an International One Health Strain Level Database to Characterise the Epidemiology of AMR Threats: ESBL—AmpC Producing E. coli as An Example …

S Perestrelo, A Amaro, MSM Brouwer, L Clemente… - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance (AMR) is one of the top public health threats nowadays. Among the
most important AMR pathogens, Escherichia coli resistant to extended spectrum …

Pathogen genomics and phage-based solutions for accurately identifying and controlling Salmonella pathogens

AV Lopez-Garcia, M AbuOun, J Nunez-Garcia… - Frontiers in …, 2023 - frontiersin.org
Salmonella is a food-borne pathogen often linked to poultry sources, causing
gastrointestinal infections in humans, with the numbers of multidrug resistant (MDR) isolates …

[HTML][HTML] Escherichia coli from six European countries reveals differences in profile and distribution of critical antimicrobial resistance determinants within One Health …

HP Kaspersen, MSM Brouwer… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background Antimicrobial resistance (AMR) is a global threat. Monitoring using an
integrated One Health approach is essential to detect changes in AMR occurrence. Aim We …

[HTML][HTML] Optimization of gene selection for cancer classification in high-dimensional data using an improved african vultures algorithm

MG Gafar, AA Abohany, AE Elkhouli, AAA El-Mageed - Algorithms, 2024 - mdpi.com
This study presents a novel method, termed RBAVO-DE (Relief Binary African Vultures
Optimization based on Differential Evolution), aimed at addressing the Gene Selection (GS) …

adhesiomeR: a tool for Escherichia coli adhesin classification and analysis

K Sidorczuk, M Burdukiewicz, K Cerk, J Fritscher… - BMC genomics, 2024 - Springer
Adhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli.
However, to date no resources have been dedicated to the detailed analysis of E. coli …

Implementation of WGS analysis of ESBL-producing Escherichia coli within EU AMR monitoring in livestock and meat

MSM Brouwer, A Zandbergen Van Essen… - Journal of …, 2023 - academic.oup.com
Background As WGS comes of age, changes in EU legislation implemented in 2021 allow its
usage for systematic monitoring of ESBL-producing Escherichia coli from livestock and …

Rapid detection and molecular epidemiology of β-lactamase producing Enterobacteriaceae isolated from food animals and in-contact humans in Nigeria

SO Olorunleke, M Kirchner, N Duggett, K Stevens… - Plos one, 2024 - journals.plos.org
The emergence and spread of β-lactamase-producing Enterobacteriaceae poses a
significant threat to public health, necessitating the rapid detection and investigation of the …

Anti-persister efficacy of colistin and meropenem against uropathogenic Escherichia coli is dependent on environmental conditions

J Urbaniec, M Getino, TBD McEwan… - …, 2023 - microbiologyresearch.org
Antibiotic persistence is a phenomenon observed when genetically susceptible cells survive
long-term exposure to antibiotics. These 'persisters' are an intrinsic component of bacterial …