Metal–organic frameworks for biological applications

I Abánades Lázaro, X Chen, M Ding… - Nature Reviews …, 2024 - nature.com
Metal–organic frameworks (MOFs) have emerged as exciting potential new candidates for
application across nanomedicine, with the first example now in a phase II human clinical …

Confining enzymes in porous organic frameworks: from synthetic strategy and characterization to healthcare applications

S Huang, G Chen, G Ouyang - Chemical Society Reviews, 2022 - pubs.rsc.org
Enzymes are a class of natural catalysts with high efficiency, specificity, and selectivity
unmatched by their synthetic counterparts and dictate a myriad of reactions that constitute …

Specific nanodrug for diabetic chronic wounds based on antioxidase-mimicking MOF-818 nanozymes

D Chao, Q Dong, Z Yu, D Qi, M Li, L Xu… - Journal of the …, 2022 - ACS Publications
Chronic wound is a common complication for diabetic patients, which entails substantial
inconvenience, persistent pain, and significant economic burden to patients. However …

Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications

R Ettlinger, U Lächelt, R Gref, P Horcajada… - Chemical Society …, 2022 - pubs.rsc.org
In the last two decades, the field of metal–organic frameworks (MOFs) has exploded, and
MOF nanoparticles in particular are being investigated with increasing interest for various …

MOF-enabled confinement and related effects for chemical catalyst presentation and utilization

J Liu, TA Goetjen, Q Wang, JG Knapp… - Chemical Society …, 2022 - pubs.rsc.org
A defining characteristic of nearly all catalytically functional MOFs is uniform, molecular-
scale porosity. MOF pores, linkers and nodes that define them, help regulate reactant and …

Metal–organic frameworks for drug delivery: a design perspective

HD Lawson, SP Walton, C Chan - ACS applied materials & …, 2021 - ACS Publications
The use of metal–organic frameworks (MOFs) in biomedical applications has greatly
expanded over the past decade due to the precision tunability, high surface areas, and high …

Metal–organic framework-based enzyme biocomposites

W Liang, P Wied, F Carraro, CJ Sumby… - Chemical …, 2021 - ACS Publications
Because of their efficiency, selectivity, and environmental sustainability, there are significant
opportunities for enzymes in chemical synthesis and biotechnology. However, as the three …

A historical overview of the activation and porosity of metal–organic frameworks

X Zhang, Z Chen, X Liu, SL Hanna, X Wang… - Chemical Society …, 2020 - pubs.rsc.org
Since the first reports of metal–organic frameworks (MOFs), this unique class of crystalline,
porous materials has garnered increasing attention in a wide variety of applications such as …

Emerging porous organic polymers for biomedical applications

Y Zhu, P Xu, X Zhang, D Wu - Chemical Society Reviews, 2022 - pubs.rsc.org
Porous organic polymers (POPs) have emerged as a new class of multifunctional porous
materials and received tremendous research attention from both academia and industry …

The uptake of metal–organic frameworks: A journey into the cell

E Linnane, S Haddad, F Melle, Z Mei… - Chemical Society …, 2022 - pubs.rsc.org
The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …