Metal–organic frameworks for biological applications

I Abánades Lázaro, X Chen, M Ding… - Nature Reviews …, 2024‏ - nature.com
Metal–organic frameworks (MOFs) have emerged as exciting potential new candidates for
application across nanomedicine, with the first example now in a phase II human clinical …

Confining enzymes in porous organic frameworks: from synthetic strategy and characterization to healthcare applications

S Huang, G Chen, G Ouyang - Chemical Society Reviews, 2022‏ - pubs.rsc.org
Enzymes are a class of natural catalysts with high efficiency, specificity, and selectivity
unmatched by their synthetic counterparts and dictate a myriad of reactions that constitute …

Specific nanodrug for diabetic chronic wounds based on antioxidase-mimicking MOF-818 nanozymes

D Chao, Q Dong, Z Yu, D Qi, M Li, L Xu… - Journal of the …, 2022‏ - ACS Publications
Chronic wound is a common complication for diabetic patients, which entails substantial
inconvenience, persistent pain, and significant economic burden to patients. However …

pH-stable MOFs: Design principles and applications

B Pramanik, R Sahoo, MC Das - Coordination Chemistry Reviews, 2023‏ - Elsevier
Metal–organic frameworks (MOFs) have been attracting tremendous attention and
recognized as one of the most promising porous materials due to their great structural …

Toxicity of metal–organic framework nanoparticles: from essential analyses to potential applications

R Ettlinger, U Lächelt, R Gref, P Horcajada… - Chemical Society …, 2022‏ - pubs.rsc.org
In the last two decades, the field of metal–organic frameworks (MOFs) has exploded, and
MOF nanoparticles in particular are being investigated with increasing interest for various …

MOF-enabled confinement and related effects for chemical catalyst presentation and utilization

J Liu, TA Goetjen, Q Wang, JG Knapp… - Chemical Society …, 2022‏ - pubs.rsc.org
A defining characteristic of nearly all catalytically functional MOFs is uniform, molecular-
scale porosity. MOF pores, linkers and nodes that define them, help regulate reactant and …

Metal–organic frameworks for drug delivery: a design perspective

HD Lawson, SP Walton, C Chan - ACS applied materials & …, 2021‏ - ACS Publications
The use of metal–organic frameworks (MOFs) in biomedical applications has greatly
expanded over the past decade due to the precision tunability, high surface areas, and high …

[HTML][HTML] Metal-organic frameworks for advanced drug delivery

S He, L Wu, X Li, H Sun, T **ong, J Liu, C Huang… - … Pharmaceutica Sinica B, 2021‏ - Elsevier
Abstract Metal-organic frameworks (MOFs), comprised of organic ligands and metal
ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their …

Metal–organic framework-based enzyme biocomposites

W Liang, P Wied, F Carraro, CJ Sumby… - Chemical …, 2021‏ - ACS Publications
Because of their efficiency, selectivity, and environmental sustainability, there are significant
opportunities for enzymes in chemical synthesis and biotechnology. However, as the three …

The uptake of metal–organic frameworks: a journey into the cell

E Linnane, S Haddad, F Melle, Z Mei… - Chemical Society …, 2022‏ - pubs.rsc.org
The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …