Implications of glial nitric oxide in neurodegenerative diseases

JE Yuste, E Tarragon, CM Campuzano… - Frontiers in cellular …, 2015 - frontiersin.org
Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

Nitric oxide signaling in brain function, dysfunction, and dementia

JR Steinert, T Chernova, ID Forsythe - The Neuroscientist, 2010 - journals.sagepub.com
Nitric oxide (NO) is an important signaling molecule that is widely used in the nervous
system. With recognition of its roles in synaptic plasticity (long-term potentiation, LTP; long …

Nitric oxide/nitric oxide synthase system in the pathogenesis of neurodegenerative disorders—an overview

OM Iova, GE Marin, I Lazar, I Stanescu, G Dogaru… - Antioxidants, 2023 - mdpi.com
Nitric oxide, a ubiquitous molecule found throughout the natural world, is a key molecule
implicated in many central and benefic molecular pathways and has a well-established role …

[HTML][HTML] The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders

MK Tripathi, M Kartawy, H Amal - Redox Biology, 2020 - Elsevier
Nitric oxide (NO) is a multifunctional signalling molecule and a neurotransmitter that plays
an important role in physiological and pathophysiological processes. In physiological …

The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders

PJ Urrutia, NP Mena, MT Núñez - Frontiers in pharmacology, 2014 - frontiersin.org
A growing set of observations points to mitochondrial dysfunction, iron accumulation,
oxidative damage and chronic inflammation as common pathognomonic signs of a number …

Reactive nitrogen species: molecular mechanisms and potential significance in health and disease

MC Martinez, R Andriantsitohaina - Antioxidants & redox signaling, 2009 - liebertpub.com
Reactive nitrogen species (RNS) are various nitric oxide–derived compounds, including
nitroxyl anion, nitrosonium cation, higher oxides of nitrogen, S-nitrosothiols, and dinitrosyl …

Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson's Disease: A Review

DS Malar, MI Prasanth, JM Brimson, R Sharika… - Molecules, 2020 - mdpi.com
Neurodegenerative disease is a collective term given for the clinical condition, which results
in progressive degeneration of neurons and the loss of functions associated with the …

Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells

PM Liy, NNA Puzi, S Jose… - … Biology and Medicine, 2021 - journals.sagepub.com
Nitric oxide is a versatile mediator formed by enzymes called nitric oxide synthases. It has
numerous homeostatic functions and important roles in inflammation. Within the inflamed …

Modulation of M1/M2 polarization by capsaicin contributes to the survival of dopaminergic neurons in the lipopolysaccharide-lesioned substantia nigra in vivo

E Bok, YC Chung, KS Kim, HH Baik, WH Shin… - … & molecular medicine, 2018 - nature.com
The present study examined the neuroprotective effects of capsaicin (CAP) and explored
their underlying mechanisms in a lipopolysaccharide (LPS)-lesioned inflammatory rat model …

Toxoplasmosis: a pathway to neuropsychiatric disorders

S Tyebji, S Seizova, AJ Hannan, CJ Tonkin - … & Biobehavioral Reviews, 2019 - Elsevier
Toxoplasma gondii is an obligate intracellular parasite that resides, in a latent form, in the
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …