[HTML][HTML] tRNA Modifications and Modifying Enzymes in Disease, the Potential Therapeutic Targets
W Cui, D Zhao, J Jiang, F Tang, C Zhang… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract tRNA is one of the most conserved and abundant RNA species, which plays a key
role during protein translation. tRNA molecules are post-transcriptionally modified by tRNA …
role during protein translation. tRNA molecules are post-transcriptionally modified by tRNA …
Anticodon stem-loop tRNA modifications influence codon decoding and frame maintenance during translation
TJ Smith, RN Giles, KS Koutmou - Seminars in Cell & Developmental …, 2024 - Elsevier
RNAs are central to protein synthesis, with ribosomal RNA, transfer RNAs and messenger
RNAs comprising the core components of the translation machinery. In addition to the four …
RNAs comprising the core components of the translation machinery. In addition to the four …
Metabolic analysis of nucleosides/bases in the urine and serum of patients with alcohol-associated liver disease
Accumulating evidence supports the important role of RNA modifications in liver disease
pathogenesis. However, RNA modifications in alcohol-associated liver disease (ALD) have …
pathogenesis. However, RNA modifications in alcohol-associated liver disease (ALD) have …
Challenges with simulating modified RNA: insights into role and reciprocity of experimental and computational approaches
RNA is critical to a broad spectrum of biological and viral processes. This functional diversity
is a result of their dynamic nature; the variety of three-dimensional structures that they can …
is a result of their dynamic nature; the variety of three-dimensional structures that they can …
Rosmarinic acid alleviates radiation-induced pulmonary fibrosis by downregulating the tRNA N7-methylguanosine modification-regulated fibroblast-to-myofibroblast …
T Zhang, J Mi, X Qin, Z Ouyang, Y Wang… - Journal of …, 2024 - Taylor & Francis
Background Radiation-induced pulmonary fibrosis (RIPF) is a common complication after
radiotherapy in thoracic cancer patients, and effective treatment methods are lacking. The …
radiotherapy in thoracic cancer patients, and effective treatment methods are lacking. The …
Adenine Methylation Enhances the Conformational Flexibility of an RNA Hairpin Tetraloop
The N6-methyladenosine modification is one of the most abundant post-transcriptional
modifications in ribonucleic acid (RNA) molecules. Using molecular dynamics simulations …
modifications in ribonucleic acid (RNA) molecules. Using molecular dynamics simulations …
Molecular dynamics simulations of chemically modified ribonucleotides
Post-transcriptional modifications are crucial for RNA function, with roles ranging from the
stabilization of functional RNA structures to modulation of RNA–protein interactions …
stabilization of functional RNA structures to modulation of RNA–protein interactions …
tRNA modification landscape sha** protein synthesis and energy production in early ectodermal differentiation
S Flad - 2024 - archiv.ub.uni-heidelberg.de
Gene expression is a multi-layered process, tightly regulated by several transcriptional and
post-transcriptional mechanisms. While transcription is regulated for example by DNA …
post-transcriptional mechanisms. While transcription is regulated for example by DNA …
[SÁCH][B] An IMS-MS/MD Workflow for Determining Higher Order Structure and Dynamics of Nucleic Acids
RJ D'Esposito - 2022 - search.proquest.com
Ion mobility spectrometry–mass spectrometry (IMS-MS) has potential for the investigation of
structure and dynamics in large biopolymers, which will come to full fruition only with a firmer …
structure and dynamics in large biopolymers, which will come to full fruition only with a firmer …
[TRÍCH DẪN][C] Inaugural dissertation for obtaining the doctoral degree of the Combined Faculty of Mathematics, Engineering and
MSS Flad