Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies

Z Zhou, Y Pang, J Ji, J He, T Liu, L Ouyang… - Nature Reviews …, 2024 - nature.com
In vitro 3D models are advanced biological tools that have been established to overcome
the shortcomings of oversimplified 2D cultures and mouse models. Various in vitro 3D …

Newly developed 3D in vitro models to study tumor–immune interaction

P Mu, S Zhou, T Lv, F ** therapeutic approach has revolutionized cancer
treatment and revitalized the field of tumor immunology research. 3D in vitro models are …

[HTML][HTML] The application of 3D bioprinting in urological diseases

K Xu, Y Han, Y Huang, P Wei, J Yin, J Jiang - Materials Today Bio, 2022 - Elsevier
Urologic diseases are commonly diagnosed health problems affecting people around the
world. More than 26 million people suffer from urologic diseases and the annual expenditure …

Methodologies, technologies, and strategies for acoustic streaming-based acoustofluidics

M Stringer, Z Zeng, X Zhang, Y Chai, W Li… - Applied Physics …, 2023 - pubs.aip.org
Acoustofluidics offers contact-free manipulation of particles and fluids, enabling their uses in
various life sciences, such as for biological and medical applications. Recently, there have …

Free‐Boundary Microfluidic Platform for Advanced Materials Manufacturing and Applications

Z Zhu, T Chen, F Huang, S Wang, P Zhu… - Advanced …, 2024 - Wiley Online Library
Microfluidics, with its remarkable capacity to manipulate fluids and droplets at the
microscale, has emerged as a powerful platform in numerous fields. In contrast to …

Next‐Generation Preclinical Functional Testing Models in Cancer Precision Medicine: CTC‐Derived Organoids

L Huang, Y Xu, N Wang, K Yi, X **, H Si… - Small …, 2024 - Wiley Online Library
Basic and clinical cancer research requires tumor models that consistently recapitulate the
characteristics of prima tumors. As ex vivo 3D cultures of patient tumor cells, patient‐derived …

Acoustic virtual 3D scaffold for direct-interacting tumor organoid–immune cell coculture systems

H Shan, M Chen, S Zhao, X Wei, M Zheng, Y Li… - Science …, 2024 - science.org
Three-dimensional (3D) cell culture has revolutionized life sciences, particularly in organoid
technologies. Traditional bioscaffold materials, however, complicate the detachment of …

Patient-derived cancer models: Valuable platforms for anticancer drug testing

S Genta, B Coburn, DW Cescon, A Spreafico - Frontiers in Oncology, 2022 - frontiersin.org
Molecularly targeted treatments and immunotherapy are cornerstones in oncology, with
demonstrated efficacy across different tumor types. Nevertheless, the overwhelming majority …

Printhead on a chip: empowering droplet-based bioprinting with microfluidics

P Zhang, C Liu, C Modavi, A Abate, H Chen - Trends in Biotechnology, 2024 - cell.com
Droplet-based bioprinting has long struggled with the manipulation and dispensation of
individual cells from a printhead, hindering the fabrication of artificial cellular structures with …

[HTML][HTML] Photocrosslinkable Biomaterials for 3D Bioprinting: Mechanisms, Recent Advances, and Future Prospects

Y Lai, X **ao, Z Huang, H Duan, L Yang… - International Journal of …, 2024 - mdpi.com
Constructing scaffolds with the desired structures and functions is one of the main goals of
tissue engineering. Three-dimensional (3D) bioprinting is a promising technology that …