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Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …
The role of s-palmitoylation in neurological diseases: implication for zDHHC family
D Liao, Y Huang, D Liu, H Zhang, X Shi, X Li… - Frontiers in …, 2024 - frontiersin.org
S-palmitoylation is a reversible posttranslational modification, and the palmitoylation
reaction in human-derived cells is mediated by the zDHHC family, which is composed of S …
reaction in human-derived cells is mediated by the zDHHC family, which is composed of S …
[HTML][HTML] In vivo and computational studies on sitagliptin's neuroprotective role in type 2 diabetes mellitus: implications for Alzheimer's disease
Background/Objectives: Diabetes mellitus (DM), a widespread endocrine disorder
characterized by chronic hyperglycemia, can cause nerve damage and increase the risk of …
characterized by chronic hyperglycemia, can cause nerve damage and increase the risk of …
Pharmacokinetic and molecular docking studies to pyrimidine drug using Mn3O4 nanoparticles to explore potential anti-Alzheimer activity
WS Shehab, HA Haikal, DA Elsayed, AF El-Farargy… - Scientific Reports, 2024 - nature.com
Alzheimer disease (AD) is the cause of dementia and accounts for 60–80% cases. Tumor
Necrosis Factor-alpha (TNF-α) is a multifunctional cytokine that provides resistance to …
Necrosis Factor-alpha (TNF-α) is a multifunctional cytokine that provides resistance to …
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment
Over the past 20 years, advances in the field of pathogenesis have inspired researchers to
look into novel pharmacological therapeutics that are more focused on the …
look into novel pharmacological therapeutics that are more focused on the …
Unveiling piperazine-quinoline hybrids as potential multi-target directed anti-Alzheimer's agents: design, synthesis and biological evaluation
Multi-target directed ligands (MTDLs) have recently been popularized due to their
outstanding efficacy in combating the complicated features of Alzheimer's disease. This …
outstanding efficacy in combating the complicated features of Alzheimer's disease. This …
Interaction between resveratrol and SIRT1: role in neurodegenerative diseases
L Zhu, M Yang, L Fan, Q Yan, L Zhang, P Mu… - Naunyn-Schmiedeberg's …, 2024 - Springer
Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and
Huntington's disease, pose significant health challenges and economic burdens worldwide …
Huntington's disease, pose significant health challenges and economic burdens worldwide …
[HTML][HTML] The influence of selected antipsychotic drugs on biochemical aspects of Alzheimer's disease
M Podsiedlik, M Markowicz-Piasecka… - International Journal of …, 2022 - mdpi.com
The aim of this study was to assess the potency of selected antipsychotic drugs (haloperidol
(HAL), bromperidol (BRMP), benperidol (BNP), penfluridol (PNF), pimozide (PIM) …
(HAL), bromperidol (BRMP), benperidol (BNP), penfluridol (PNF), pimozide (PIM) …
Recent update on the development of leucine-rich repeat kinase 2 (LRRK2) inhibitors: A promising target for the treatment of Parkinson's disease
Parkinson's disease is a relatively common neurological disorder with incidence increasing
with age. Since current medications only relieve the symptoms and do not change the …
with age. Since current medications only relieve the symptoms and do not change the …
Homalothecium philippeanum (Spruce) Schimp.(Bryophyta) ekstresinin Asetilkolinesteraz enzim aktivitesine etkisi
Objective: Alzheimer's disease is the most common neurological disorder, affecting
approximately 50 million people. According to the cholinergic hypothesis, the decrease in …
approximately 50 million people. According to the cholinergic hypothesis, the decrease in …