The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a
physiological organ biomimetic system built on a microfluidic chip. Through a combination of …

Multiorgan-on-a-chip (multi-OoC) platforms have great potential to redefine the way in which
human health research is conducted. After briefly reviewing the need for comprehensive …

Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …

Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …

Hepatology and drug development for liver diseases require in vitro liver models. Typical
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …

Over the last few years, the intestine has been extensively studied using in vitro microfluidic
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …

Electrochemical aptamer-based sensors are typically deployed as individual, passive,
surface-functionalized electrodes, but they exhibit limited sensitivity especially when the …

The poor predictability of human liver toxicity is still causing high attrition rates of drug
candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing …

Microfluidic organ-on-a-chip (Organ Chip) cell culture devices are often fabricated using
polydimethylsiloxane (PDMS) because it is biocompatible, transparent, elastomeric, and …