Organ-on-a-chip: Recent breakthroughs and future prospects
Q Wu, J Liu, X Wang, L Feng, J Wu, X Zhu… - Biomedical engineering …, 2020 - Springer
The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a
physiological organ biomimetic system built on a microfluidic chip. Through a combination of …
physiological organ biomimetic system built on a microfluidic chip. Through a combination of …
Multiorgan-on-a-chip: a systemic approach to model and decipher inter-organ communication
N Picollet-D'hahan, A Zuchowska, I Lemeunier… - Trends in …, 2021 - cell.com
Multiorgan-on-a-chip (multi-OoC) platforms have great potential to redefine the way in which
human health research is conducted. After briefly reviewing the need for comprehensive …
human health research is conducted. After briefly reviewing the need for comprehensive …
Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …
biomedical application for microfluidic based devices has emerged in recent years and …
Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
Organ‐on‐a‐Chip Systems: microengineering to biomimic living systems
“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …
biomimetic principles to create key aspects of living organs faithfully, including critical …
[HTML][HTML] Gut-on-a-chip: Mimicking and monitoring the human intestine
Over the last few years, the intestine has been extensively studied using in vitro microfluidic
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …
Engineered liver-on-a-chip platform to mimic liver functions and its biomedical applications: A review
J Deng, W Wei, Z Chen, B Lin, W Zhao, Y Luo, X Zhang - Micromachines, 2019 - mdpi.com
Hepatology and drug development for liver diseases require in vitro liver models. Typical
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …
models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte …
A critical perspective on 3D liver models for drug metabolism and toxicology studies
The poor predictability of human liver toxicity is still causing high attrition rates of drug
candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing …
candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing …
Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing
Electrochemical aptamer-based sensors are typically deployed as individual, passive,
surface-functionalized electrodes, but they exhibit limited sensitivity especially when the …
surface-functionalized electrodes, but they exhibit limited sensitivity especially when the …
Simulating drug concentrations in PDMS microfluidic organ chips
Microfluidic organ-on-a-chip (Organ Chip) cell culture devices are often fabricated using
polydimethylsiloxane (PDMS) because it is biocompatible, transparent, elastomeric, and …
polydimethylsiloxane (PDMS) because it is biocompatible, transparent, elastomeric, and …