The immune system responds to cancer in two main ways. First, there are prewired
responses involving myeloid cells, innate lymphocytes and innate-like adaptive lymphocytes …

IL-17A–producing γδ T cells in mice consist primarily of Vγ6+ tissue-resident cells and Vγ4+
circulating cells. How these γδ T cell subsets are regulated during homeostasis and cancer …

Lymphocytes spanning the entire innate-adaptive spectrum can stably reside in tissues and
constitute an integral component of the local defense network against immunological …

γδ T cells are unconventional T cells, distinguished from αβ T cells in a number of functional
properties. Being small in number compared to αβ T cells, γδ T cells have surprised us with …

Gamma delta T cells play a crucial role in anti-tumor immunity due to their cytotoxic
properties. However, the role and extent of γδ T cells in production of pro-tumorigenic …

There are 2 types of T cells: αβ and γδ T cells, named based on the composition of the T-cell
receptor. γδ T cells are rare, making up 0.5%–10% of T cells. Although most leukemias …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and the high
heterogeneity of its tumor immune microenvironment (TME) is often a key reason for poor …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that presents significant
therapeutic challenges due to the absence of estrogen receptor (ER), progesterone receptor …

γδ T-cells are a rare population of T-cells with both adaptive and innate-like properties.
Despite their low prevalence, they have been found to be implicated various human …

Abstract γδT cells are unconventional T cells only accounting for 1–5% of circulating T
lymphocytes. Their potent anti-tumor capability has been evidenced by accumulating …