Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels and can be
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …

Nicotinic acetylcholine receptors (nAChRs) are actively being investigated as therapeutic
targets for the treatment of pain and inflammation, but despite more than 30 years of …

Nicotinic acetylcholine receptors (nAChRs) on dopaminergic (DA) and GABAergic (Gaba)
projection neurons of the substantia nigra (SN) and ventral tegmental area (VTA) are …

The α3 subunit of the neuronal nicotinic acetylcholine receptor is widely expressed in
autonomic ganglia and in some parts of the brain. The α3 subunit can form heteromultimeric …

Transcripts for the β2 and the β4 nicotinic acetylcholine receptor (nAChR) subunits are
found throughout the CNS and the peripheral nervous system. These two β subunits can …

Studies on the expression and cellular function of sigma receptors in autonomic neurons
were conducted in neonatal rat intracardiac and superior cervical (SCG) ganglia. Individual …

Chloride (Cl−) homeostasis is critical for many cell functions including cell signaling and
volume regulation. The action of GABA at GABAA receptors is primarily determined by the …

Vanilloid receptors are activated by capsaicin, the pungent ingredient in hot pepper. They
are also specifically and competitively inhibited by capsazepine (CPZ). To determine …

We stably transfected human kidney embryonic 293 cells with the rat neuronal nicotinic
acetylcholine receptor (nAChR) α3 and β4 subunit genes. This new cell line, KXα3β4R2 …

T lymphocyte infiltration with immunotherapy potentially suppresses most devastating brain
tumors. However, local immune privilege and tumor heterogeneity usually limit the …