Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

High-intensity exercise and mitochondrial biogenesis: current controversies and future research directions

DJ Bishop, J Botella, AJ Genders, MJC Lee… - …, 2019 - journals.physiology.org
It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …

Exercise training response heterogeneity: physiological and molecular insights

LM Sparks - Diabetologia, 2017 - Springer
The overall beneficial effects of exercise are well studied, but why some people do not
respond favourably to exercise is less understood. The National Institutes of Health …

Superior intrinsic mitochondrial respiration in women than in men

DA Cardinale, FJ Larsen, TA Schiffer… - Frontiers in …, 2018 - frontiersin.org
Sexual dimorphism is apparent in humans, however, to date no studies have investigated
mitochondrial function focusing on intrinsic mitochondrial respiration (ie, mitochondrial …

Changes in fat oxidation in response to various regimes of high intensity interval training (HIIT)

TA Astorino, MM Schubert - European journal of applied physiology, 2018 - Springer
Increased whole-body fat oxidation (FOx) has been consistently demonstrated in response
to moderate intensity continuous exercise training. Completion of high intensity interval …

Coordination of mitochondrial biogenesis by PGC-1α in human skeletal muscle: A re-evaluation

H Islam, BA Edgett, BJ Gurd - Metabolism, 2018 - Elsevier
The transcriptional co-activator peroxisome proliferator-activated receptor gamma co-
activator-1 alpha (PGC-1α) is proposed to coordinate skeletal muscle mitochondrial …

[HTML][HTML] Skeletal muscle mechanisms contributing to improved glycemic control following intense interval exercise and training

H Islam, JB Gillen - Sports Medicine and Health Science, 2023 - Elsevier
High-intensity and sprint interval training (HIIT and SIT, respectively) enhance insulin
sensitivity and glycemic control in both healthy adults and those with cardiometabolic …

Supplements and nutritional interventions to augment high-intensity interval training physiological and performance adaptations—A narrative review

SC Forbes, DG Candow, AE Smith-Ryan, KR Hirsch… - Nutrients, 2020 - mdpi.com
High-intensity interval training (HIIT) involves short bursts of intense activity interspersed by
periods of low-intensity exercise or rest. HIIT is a viable alternative to traditional continuous …

A systematic review and meta-analysis of the SIRT1 response to exercise

CG Juan, KB Matchett, GW Davison - Scientific Reports, 2023 - nature.com
Abstract Sirtuin 1 (SIRT1) is a key physiological regulator of metabolism and a target of
therapeutic interventions for cardiometabolic and ageing-related disorders. Determining the …

[HTML][HTML] Physiological basis of brief, intense interval training to enhance maximal oxygen uptake: a mini-review

MJ Gibala, MJ MacInnis - American Journal of Physiology …, 2022 - journals.physiology.org
Brief, intense interval training describes a style of exercise characterized by short bouts of
strenuous effort interspersed with recovery periods. The method increases whole body …