Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Chagas disease, caused by Trypanosoma cruzi, is treated with only two drugs;
benznidazole and nifurtimox. These drugs have some disadvantages, including their …

Protozoan diseases continue to be a worldwide social and economic health problem.
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …

One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

There is an urgent need for new, safer, and effective treatments for the diseases caused by
the protozoan parasites Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. In …

Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …

Chagas disease (CD) is a tropical neglected illness, affecting mainly populations of low
socioeconomic status in Latin America. An estimated 6 to 8 million people worldwide are …

Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a parasitic
infection that usually progresses to coma and death unless treated. WHO has updated its …

A critical review of the development of specific chemotherapeutic approaches for the
management of American Trypanosomiasis or Chagas disease is presented, including …

The concept of disease-specific chemotherapy was developed a century ago. Dyes and
arsenical compounds that displayed selectivity against trypanosomes were central to this …