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The search for noise-induced cochlear synaptopathy in humans: Mission impossible?
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
Occupational noise: auditory and non-auditory consequences
Occupational noise exposure accounts for approximately 16% of all disabling hearing
losses, but the true value and societal costs may be grossly underestimated because current …
losses, but the true value and societal costs may be grossly underestimated because current …
Hidden hearing loss? No effect of common recreational noise exposure on cochlear nerve response amplitude in humans
This study tested hypothesized relationships between noise exposure and auditory deficits.
Both retrospective assessment of potential associations between noise exposure history and …
Both retrospective assessment of potential associations between noise exposure history and …
Hidden hearing loss: a disorder with multiple etiologies and mechanisms
DC Kohrman, G Wan… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Hidden hearing loss (HHL), a recently described auditory disorder, has been proposed to
affect auditory neural processing and hearing acuity in subjects with normal audiometric …
affect auditory neural processing and hearing acuity in subjects with normal audiometric …
[HTML][HTML] Impaired speech perception in noise with a normal audiogram: No evidence for cochlear synaptopathy and no relation to lifetime noise exposure
In rodents, noise exposure can destroy synapses between inner hair cells and auditory
nerve fibers (“cochlear synaptopathy”) without causing hair cell loss. Noise-induced …
nerve fibers (“cochlear synaptopathy”) without causing hair cell loss. Noise-induced …
Middle ear muscle reflex and word recognition in “normal-hearing” adults: evidence for cochlear synaptopathy?
AM Mepani, SA Kirk, KE Hancock, K Bennett… - Ear and …, 2020 - journals.lww.com
Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …
'Normal'hearing thresholds and fundamental auditory grou** processes predict difficulties with speech-in-noise perception
E Holmes, TD Griffiths - Scientific reports, 2019 - nature.com
Understanding speech when background noise is present is a critical everyday task that
varies widely among people. A key challenge is to understand why some people struggle …
varies widely among people. A key challenge is to understand why some people struggle …
Electrophysiological markers of cochlear function correlate with hearing-in-noise performance among audiometrically normal subjects
KJ Grant, AM Mepani, P Wu… - Journal of …, 2020 - journals.physiology.org
Hearing loss caused by noise exposure, ototoxic drugs, or aging results from the loss of
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …
Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-in-noise intelligibility
Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …
Effects of noise exposure on auditory brainstem response and speech-in-noise tasks: A review of the literature
CG Le Prell - International journal of audiology, 2019 - Taylor & Francis
Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …