The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

KS Swanson, GR Gibson, R Hutkins… - Nature Reviews …, 2020 - nature.com
Abstract In May 2019, the International Scientific Association for Probiotics and Prebiotics
(ISAPP) convened a panel of nutritionists, physiologists and microbiologists to review the …

Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism

DJ Morrison, T Preston - Gut microbes, 2016 - Taylor & Francis
The formation of SCFA is the result of a complex interplay between diet and the gut
microbiota within the gut lumen environment. The discovery of receptors, across a range of …

Human gut microbes impact host serum metabolome and insulin sensitivity

HK Pedersen, V Gudmundsdottir, HB Nielsen… - Nature, 2016 - nature.com
Insulin resistance is a forerunner state of ischaemic cardiovascular disease and type 2
diabetes. Here we show how the human gut microbiome impacts the serum metabolome …

Gut microbiota in cardiovascular health and disease

WHW Tang, T Kitai, SL Hazen - Circulation research, 2017 - Am Heart Assoc
Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …

Gut microbiota are related to Parkinson's disease and clinical phenotype

F Scheperjans, V Aho, PAB Pereira… - Movement …, 2015 - Wiley Online Library
In the course of Parkinson's disease (PD), the enteric nervous system (ENS) and
parasympathetic nerves are amongst the structures earliest and most frequently affected by …

Gut microbiome and its role in colorectal cancer

M Rebersek - BMC cancer, 2021 - Springer
Colorectal cancer (CRC) is still one of the most common types of cancer in the world, and
the gut microbiome plays an important role in its development. The microbiome is involved …

Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism

A Wahlström, SI Sayin, HU Marschall, F Bäckhed - Cell metabolism, 2016 - cell.com
The gut microbiota is considered a metabolic" organ" that not only facilitates harvesting of
nutrients and energy from the ingested food but also produces numerous metabolites that …

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

A Cattaneo, N Cattane, S Galluzzi, S Provasi… - Neurobiology of …, 2017 - Elsevier
The pathway leading from amyloid-β deposition to cognitive impairment is believed to be a
cornerstone of the pathogenesis of Alzheimer's disease (AD). However, what drives amyloid …

The microbiome and cancer

RF Schwabe, C Jobin - Nature Reviews Cancer, 2013 - nature.com
Microbiota and host form a complex'super-organism'in which symbiotic relationships confer
benefits to the host in many key aspects of life. However, defects in the regulatory circuits of …

Gut microbiota modulation of chemotherapy efficacy and toxicity

JL Alexander, ID Wilson, J Teare, JR Marchesi… - Nature reviews …, 2017 - nature.com
Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …