[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications

H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Bone repair biomaterials: a perspective from immunomodulation

Y Wang, H Zhang, Y Hu, Y **g… - Advanced Functional …, 2022 - Wiley Online Library
With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

Targeted and responsive biomaterials in osteoarthritis

J Li, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Alendronate triggered dual‐cascade targeting prodrug nanoparticles for enhanced tumor penetration and STING activation of osteosarcoma

M Shen, Y Wang, T Bing, Y Tang… - Advanced Functional …, 2023 - Wiley Online Library
The complex physiological environment in bone tissue poses a challenge to the efficient
delivery of chemotherapeutic agents for osteosarcoma (OS) treatment; hence, an efficient …

Bone‐targeted exosomes: strategies and applications

J Wang, X Li, S Wang, J Cui, X Ren… - Advanced Healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

Small joint organoids 3D bioprinting: construction strategy and application

Y Zhang, G Li, J Wang, F Zhou, X Ren, J Su - Small, 2024 - Wiley Online Library
Osteoarthritis (OA) is a chronic disease that causes pain and disability in adults, affecting≈
300 million people worldwide. It is caused by damage to cartilage, including cellular …

Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Glucose oxidase‐instructed biomineralization of calcium‐based biomaterials for biomedical applications

LH Fu, C Qi, T Sun, K Huang, J Lin, P Huang - Exploration, 2023 - Wiley Online Library
In recent years, glucose oxidase (GOx) has aroused great research interest in the treatment
of diseases related to abnormal glucose metabolisms like cancer and diabetes. However, as …

Reactive oxygen species-scavenging nanomaterials for the prevention and treatment of age-related diseases

Y Dai, Y Guo, W Tang, D Chen, L Xue, Y Chen… - Journal of …, 2024 - Springer
With increasing proportion of the elderly in the population, age-related diseases (ARD) lead
to a considerable healthcare burden to society. Prevention and treatment of ARD can …

Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies

S Cao, Y Wei, H Xu, J Weng, T Qi, F Yu, S Liu… - Frontiers in …, 2023 - frontiersin.org
Purpose Recent scientific reports have revealed a close association between ferroptosis
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …