Diabetic retinopathy (DR) impairs vision of patients with type 1 and type 2 diabetes,
associated with vascular dysfunction and occlusion, retinal edema, hemorrhage, and …

Background Diabetic retinopathy is a major complication of diabetes mellitus, where in its
most advanced form ischemic changes lead to the development of retinal …

Diabetic retinopathy (DR) is a sight-threatening complication of both type-1 and type-2
diabetes. The recent success of treatments inhibiting the function of vascular endothelial …

Angiogenesis (the growth of new blood vessels) is essential in most of the body's
physiological processes, such as in the normal functioning of the endometrium during and …

The human vitreous humour (VH) is a transparent, highly hydrated gel, which occupies the
posterior segment of the eye between the lens and the retina. Physiological and …

This study aimed at examining the presence and role of chemokines (angiogenic
CCL2/MCP-1 and angiostatic CXCL4/PF-4, CXCL9/Mig, CXCL10/IP-10) in proliferative …

Purpose To identify the protein profiles in vitreous associated with retinal fibrosis,
angiogenesis, and neurite formation in epiretinal fibrovascular membranes (FVMs) in …

Numerous age-dependent alterations at the molecular, cellular, tissue and organ systems
levels underlie the pathophysiology of aging. Herein, the focus is upon the secreted protein …

Background and Purpose Hypoxia‐mediated neovascularization plays an important role in
age‐related macular degeneration (AMD). There are few animal models or effective …

Abstract Alpha-1 antitrypsin (A1AT) is a protease inhibitor in the serum. Its primary function is
to inhibit the activity of a series of proteases, including proteinase 3, neutrophil elastase …