Background The development of resistance is a problem shared by both classical
chemotherapy and targeted therapy. Patients may respond well at first, but relapse is …

Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …

Background Multimarker quantitative real‐time polymerase chain reaction (qRT‐PCR)
represents an effective method for detecting circulating tumour cells in the peripheral blood …

Background Knowledge of the genotype of melanoma is important to guide patient
management. Identification of mutations in BRAF and c-KIT lead directly to targeted …

Abstract Background Mutations of BRAF, NRAS and c‐KIT oncogenes are preferentially
described in certain histological subtypes of melanoma and linked to specific …

Melanoma patients experience inferior survival after biochemotherapy when their tumors
contain numerous cells expressing the inducible isoform of NO synthase (iNOS) and …

The stress-inducible chaperone protein HSP70 (HSPA1) is implicated in melanoma
development, and HSP70 inhibitors exert tumor-specific cytotoxic activity in cancer. In this …

Melanoma is a highly invasive cancer that resists most conventional treatments. Therefore,
there is an urgent need to identify alternative anticancer agents able to affect new molecular …

Several literature has shown that salinomycin (Sal) is able to kill various types of cancer
cells through different signaling pathways. However, its effect on melanoma has seldom …

Till date scientists are struggling to understand the complete mechanism of carcinogenesis.
In future, the real time detection of cancer may help scientists to identify some of the …