Towards hepatitis C virus elimination: Egyptian experience, achievements and limitations

D Omran, M Alboraie, RA Zayed… - World journal of …, 2018‏ - pmc.ncbi.nlm.nih.gov
Worldwide, more than one million people die each year from hepatitis C virus (HCV) related
diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt …

Viral hepatitis C therapy: pharmacokinetic and pharmacodynamic considerations: a 2019 update

EJ Smolders, AME Jansen, PGJ Ter Horst… - Clinical …, 2019‏ - Springer
It has been estimated by the World Health Organization (WHO) that over 71 million people
were infected with the hepatitis C virus (HCV) in 2015. Since then, a number of highly …

Real-world effectiveness and safety of sofosbuvir and nonstructural protein 5A inhibitors for chronic hepatitis C genotype 1, 2, 3, 4, or 6: a multicentre cohort study

P Charatcharoenwitthaya, V Wongpaitoon… - BMC …, 2020‏ - Springer
Background We investigated real-world effectiveness and safety of sofosbuvir and the
nonstructural protein 5A inhibitors in the treatment of patients infected with hepatitis C virus …

Safety and efficacy of combined sofosbuvir/daclatasvir treatment of children and adolescents with chronic hepatitis C genotype 4

TY Abdel Ghaffar, S El Naghi… - Journal of viral …, 2019‏ - Wiley Online Library
Direct‐acting antivirals have become available for treating chronic HCV (hepatitis C virus)
infection in adults and, recently, in children at least 12 years old. Our aim was to investigate …

Efficacy and safety of sofosbuvir plus daclatasvir with or without ribavirin: large real-life results of patients with chronic hepatitis C genotype 4

A Abdel-Moneim, A Aboud, M Abdel-Gabaar… - Hepatology …, 2018‏ - Springer
Background and aim Clinical studies evaluating the efficacy of daclatasvir (DCV) for
treatment of chronic hepatitis C virus (HCV) genotype 4 (GT4) infection are scarce. This …

[HTML][HTML] Interleukin 28B Polymorphism as a Predictor of Sustained Virological Response to Sofosbuvir-Based Therapy for Hepatitis C Virus Patients

SM Zaki, HS Ahmed, MM Yousif, EM Awad - Tropical Medicine and …, 2022‏ - mdpi.com
In various genome-wide correlation studies, interleukin (IL) 28B gene polymorphism has
been strongly correlated with both the therapeutic and spontaneous mediated clearance of …

Treatment of hepatitis C virus genotype 4 in the DAA era

A Di Biagio, L Taramasso, G Cenderello - Virology journal, 2018‏ - Springer
The recently approved interferon-free DAA (direct antiviral agents) regimens have shown not
only to be effective in terms of sustained virological response (SVR) rates (> 90%) but also …

Era of direct acting anti-viral agents for the treatment of hepatitis C

M Ahmed - World journal of hepatology, 2018‏ - pmc.ncbi.nlm.nih.gov
Hepatitis C infection is universal and the most common indication of liver transplantation in
the United States. The period of less effective interferon therapy with intolerable side effects …

Effectiveness of 8-week sofosbuvir/ledipasvir in the adolescent chronic hepatitis C-infected patients

H El-Khayat, EM Kamal, M Yakoot… - European journal of …, 2019‏ - journals.lww.com
Background The sustained virological response (SVR) rate for the 12-week sofosbuvir
(SOF)/ledipasvir (LVD) treatment of adolescent genotype-4 patients is high. The aim of this …

Predictive value of CONUT score combined with serum CA199 levels in postoperative survival of patients with pancreatic ductal adenocarcinoma: a retrospective …

A Wang, B Sun, M Wang, H Shi, Z Huang, T He, Q Li… - PeerJ, 2020‏ - peerj.com
Background The preoperative controlling nutritional status (CONUT) score and serum
carbohydrate antigen 199 (CA199) levels are individually correlated with the prognosis of …