The vaccines developed over the first two hundred years since Jenner's lifetime have
accomplished striking reductions of infection and disease wherever applied. Pasteur's early …

Toll-like receptors (TLRs) have first been characterized for their capacity to detect conserved
microbial components like lipopolysaccharide (LPS) and double-stranded RNA, resulting in …

Despite the development of highly effective prophylactic vaccines against human
papillomavirus (HPV) serotypes 16 and 18, prevention of cervical dysplasia and cancer in …

Historically, the name of natural killer (NK) cells came from their natural ability to kill tumor
cells in vitro. From the 1970s to date, accumulating data highlighted the importance of NK …

We contrast the efforts to treat ovarian cancer and cervical cancer through vaccination
because of their different pathobiology. A plethora of approaches have been developed for …

Detection of human papillomavirus (HPV) in head and neck cancer has therapeutic
implications. In situ hybridization and immunohistochemistry for p16 are used by surgical …

Background: Cervical cancer is the second largest cause of cancer deaths in women
worldwide. It is now evident that persistent infection with high-risk human papillomavirus …

In 2014 and 2021, two nucleic-acid vaccine candidates named MAV E2 and VGX-3100
completed phase III clinical trials in Mexico and US, respectively, for patients with human …

Prophylactic vaccines capable of preventing human papillomavirus (HPV) infections are still
inaccessible to a vast majority of the global population due to their high cost and challenges …

Human papillomavirus (HPV) is widely known as a cause of cervical cancer (CC) and
cervical intraepithelial neoplasia (CIN). HPVs related to cancer express two main …