Stress has long been suggested to be an important correlate of uncontrolled drinking and
relapse. An important hormonal response system to stress—the hypothalamic–pituitary …

Bruce McEwen's discovery of receptors for corticosterone in the rat hippocampus introduced
higher brain circuits in the neuroendocrinology of stress. Subsequently, these receptors …

The mineralocorticoid receptor (MR) and its ligand aldosterone are the principal modulators
of hormone-regulated renal sodium reabsorption. In addition to the kidney, there are several …

Stress and stress-related health impairments are major problems in human life and
elucidating the biological pathways linking stress and disease is of substantial importance …

Cumulative acute psychosocial stress is thought to promote the development of a range of
disorders which suggests that biomarkers for the physiological response may become …

Stress is one of the most significant health problems in modern societies and the 21st
century. This explains a pressing need for investigations into the biological pathways linking …

BACKGROUND: Preclinical research findings suggest that exposure to stress and
concomitant hypothalamus-pituitary-adrenal (HPA) axis activation during early development …

Stress is defined as a state of perturbed homeostasis following endangerment that evokes
manifold adaptive reactions, which are summarized as the stress response. In the case of …

Chronic psychosocial stress is increasingly being recognised as a risk factor for sporadic
Alzheimer's disease (AD). The hypothalamic–pituitary–adrenal axis (HPA axis) is the major …

Resilience refers to the ability to successfully adapt to stressors, maintaining psychological
well-being in the face of adversity. Recent years have seen a great deal of research into the …