SOX transcription factors as important regulators of neuronal and glial differentiation during nervous system development and adult neurogenesis

M Stevanovic, D Drakulic, A Lazic… - Frontiers in molecular …, 2021 - frontiersin.org
The SOX proteins belong to the superfamily of transcription factors (TFs) that display
properties of both classical TFs and architectural components of chromatin. Since the …

Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer

A Ghosh, WDW Heston - Journal of cellular biochemistry, 2004 - Wiley Online Library
Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein,
which is overexpressed manifold on prostate cancer as well as neovasculature of most of …

Identification of common genetic risk variants for autism spectrum disorder

J Grove, S Ripke, TD Als, M Mattheisen, RK Walters… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

Aberrant Wnt/β-catenin pathway activation in idiopathic pulmonary fibrosis

M Chilosi, V Poletti, A Zamò, M Lestani… - The American journal of …, 2003 - Elsevier
To investigate the molecular events that may underpin dysfunctional repair processes that
characterize idiopathic pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP), we …

Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families

GE Schepers, RD Teasdale, P Koopman - Developmental cell, 2002 - cell.com
SOX5P (Table 2). Other fragments corresponding to al., 2000) has been exploited in many
laboratories to parts of SOX2,-17,-20, and-30 can be found in the identify approximately 30 …

Development and differentiation of the intestinal epithelium

P de Santa Barbara, GR Van Den Brink… - Cellular and Molecular …, 2003 - Springer
The gastrointestinal tract develops from a simple tube to a complex organ with patterns of
differentiation along four axes of asymmetry. The organ is composed of all three germ layers …

Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors

V Lefebvre, B Dumitriu, A Penzo-Méndez, Y Han… - The international journal …, 2007 - Elsevier
Maintain stemness, commit to a specific lineage, differentiate, proliferate, or die. These are
essential decisions that every cell is constantly challenged to make in multi-cellular …

Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

M Kennedy, SL D'Souza, M Lynch-Kattman… - Blood, 2007 - ashpublications.org
The onset of hematopoiesis in the mouse embryo and in the embryonic stem (ES) cell
differentiation model is defined by the emergence of the hemangioblast, a progenitor with …

Transcriptional control of lung morphogenesis

Y Maeda, V Dave, JA Whitsett - Physiological reviews, 2007 - journals.physiology.org
The vertebrate lung consists of multiple cell types that are derived primarily from endodermal
and mesodermal compartments of the early embryo. The process of pulmonary …

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer

Y Chen, L Shi, L Zhang, R Li, J Liang, W Yu… - Journal of Biological …, 2008 - jbc.org
SOX genes encode a family of high-mobility group transcription factors that play critical roles
in organogenesis. The functional specificity of different SOX proteins and the tissue …