Ionizing radiation is commonly used to treat a number of malignancies. Although highly
effective and now more targeted, many patients suffer side effects. The number of cancer …

Chronic radiation enteritis is an increasing problem, as more patients receive radiotherapy
as part of their cancer therapy and as the long-term survival of these patients improves. This …

Radiation-induced fibrosis (RIF) and radionecrosis (RN) are late complications that are
usually considered irreversible. Usual management strategy includes eliminating local and …

This review summarizes the current state of knowledge regarding the role of endothelial
dysfunction in the pathogenesis of early and delayed intestinal radiation toxicity and …

Aim: To systematically review the prophylactic and therapeutic interventions for reducing the
incidence or severity of intestinal symptoms among cancer patients receiving radiotherapy …

Despite the potential devastating health consequences of intense total-body irradiation, and
the decades of research, there still remains a dearth of safe and effective radiation …

Radiation enteritis continues to be a major health concern in recipients of radiation therapy.
The incidence of radiation enteritis is expected to continue to rise during the coming years …

PURPOSE: Radiation-induced heart disease (RIHD) is a severe side effect of thoracic
radiotherapy. This study examined the effects of pentoxifylline (PTX) and α-tocopherol on …

Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy.
Although many cases resolve spontaneously, some lead to chronic symptoms including …

Radiation-induced fibrosis in the head and neck is a well-established pathophysiological
process after radiotherapy. Recently pentoxifylline and tocopherol have been proposed as …