Pseudogene-derived lncRNAs and their miRNA sponging mechanism in human cancer
W Lou, B Ding, P Fu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Pseudogenes, abundant in the human genome, are traditionally considered as non-
functional “junk genes.” However, recent studies have revealed that pseudogenes act as key …
functional “junk genes.” However, recent studies have revealed that pseudogenes act as key …
On the immortality of television sets:“function” in the human genome according to the evolution-free gospel of ENCODE
A recent slew of ENCyclopedia Of DNA Elements (ENCODE) Consortium publications,
specifically the article signed by all Consortium members, put forward the idea that more …
specifically the article signed by all Consortium members, put forward the idea that more …
An evolutionary classification of genomic function
The pronouncements of the ENCODE Project Consortium regarding “junk DNA” exposed the
need for an evolutionary classification of genomic elements according to their selected-effect …
need for an evolutionary classification of genomic elements according to their selected-effect …
Deep transcriptome sequencing provides new insights into the structural and functional organization of the wheat genome
Background Because of its size, allohexaploid nature, and high repeat content, the bread
wheat genome is a good model to study the impact of the genome structure on gene …
wheat genome is a good model to study the impact of the genome structure on gene …
dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease
Although thousands of pseudogenes have been annotated in the human genome, their
transcriptional regulation, expression profiles and functional mechanisms are largely …
transcriptional regulation, expression profiles and functional mechanisms are largely …
Pseudogenes and their genome-wide prediction in plants
Pseudogenes are paralogs generated from ancestral functional genes (parents) during
genome evolution, which contain critical defects in their sequences, such as lacking a …
genome evolution, which contain critical defects in their sequences, such as lacking a …
[HTML][HTML] A disparate role of RP11-424C20. 2/UHRF1 axis through control of tumor immune escape in liver hepatocellular carcinoma and thymoma
J Yang, Y Zhang, H Song - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
The immune system is critical in modulating cancer progression. Pseudogenes are a special
type of long non-coding RNAs that regulate different tumorigenic processes. However, the …
type of long non-coding RNAs that regulate different tumorigenic processes. However, the …
Unravelling the due importance of pseudogenes and their resurrection in plants
The complexities of a genome are underpinned to the vast expanses of the intergenic
region, which constitutes∼ 97–98% of the genome. This region is essentially composed of …
region, which constitutes∼ 97–98% of the genome. This region is essentially composed of …
FTH1P3, a novel H-ferritin pseudogene transcriptionally active, is ubiquitously expressed and regulated during cell differentiation
Ferritin, the major iron storage protein, performs its essential functions in the cytoplasm,
nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light …
nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light …
Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to Trypanosoma cruzi strains of high and low virulence
Abstract Background Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma
cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic …
cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic …