Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2
DJ Drucker, B Yusta - Annual review of physiology, 2014 - annualreviews.org
Glucagon-like peptide-2 (GLP-2) is a 33-amino-acid proglucagon-derived peptide secreted
from enteroendocrine L cells. GLP-2 circulates at low basal levels in the fasting period, and …
from enteroendocrine L cells. GLP-2 circulates at low basal levels in the fasting period, and …
Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
Gut peptides exert diverse effects regulating satiety, gastrointestinal motility and acid
secretion, epithelial integrity, and both nutrient absorption and disposal. These actions are …
secretion, epithelial integrity, and both nutrient absorption and disposal. These actions are …
a comparison of glucagon‐like peptides 1 and 2
P Janssen, A Rotondo, F Mulé… - Alimentary pharmacology …, 2013 - Wiley Online Library
Background Recent advancements in understanding the roles and functions of glucagon‐
like peptide 1 (GLP‐1) and 2 (GLP‐2) have provided a basis for targeting these peptides in …
like peptide 1 (GLP‐1) and 2 (GLP‐2) have provided a basis for targeting these peptides in …
Glucagon-like peptide-2 induces intestinal adaptation in parenterally fed rats with short bowel syndrome
GR Martin, LE Wallace… - American Journal of …, 2004 - journals.physiology.org
Glucagon-like peptide-2 (GLP-2) is an intestinal trophic enteroendocrine peptide that is
associated with intestinal adaptation following resection. Herein, we investigate the effects of …
associated with intestinal adaptation following resection. Herein, we investigate the effects of …
Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease
TA Perry, NH Greig - Current Alzheimer Research, 2005 - ingentaconnect.com
Glucagon-like peptide-1 (7-36)-amide (GLP-1) is an endogenous insulinotropic peptide that
is secreted from the gastrointestinal tract in response to food. It enhances pancreatic islet β …
is secreted from the gastrointestinal tract in response to food. It enhances pancreatic islet β …
Ciliary neurotrophic factor recruitment of glucagon‐like peptide‐1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
The distinct lack of cell lines derived from the adult brain is evident. Ciliary neurotrophic
factor (CNTF) triggers neurogenesis in primary culture from adult mouse hypothalamus, as …
factor (CNTF) triggers neurogenesis in primary culture from adult mouse hypothalamus, as …
Glucagon-like peptide-2
▪ Abstract Multiple peptide hormones produced within the gastrointestinal system aid in the
regulation of energy homeostasis and metabolism. Among these is the intestinotrophic …
regulation of energy homeostasis and metabolism. Among these is the intestinotrophic …
A new Alzheimer's disease interventive strategy: GLP-1
TA Perry, NH Greig - Current drug targets, 2004 - ingentaconnect.com
Glucagon-like peptide-1 (7-36)-amide (GLP-1) is an endogenous 30-amino acid gut peptide,
which binds at the GLP-1 receptor coupled to the cyclic AMP second messenger pathway …
which binds at the GLP-1 receptor coupled to the cyclic AMP second messenger pathway …
Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration
N El-Jamal, E Erdual, M Neunlist… - American Journal …, 2014 - journals.physiology.org
The glucagon-like peptide 2 (GLP-2) is an intestinotrophic hormone with growth promoting
and anti-inflammatory actions. However, the full biological functions of GLP-2 and the …
and anti-inflammatory actions. However, the full biological functions of GLP-2 and the …
Roles of gastrointestinal polypeptides in intestinal barrier regulation
X **e, C Geng, X Li, J Liao, Y Li, Y Guo, C Wang - Peptides, 2022 - Elsevier
The intestinal barrier is a dynamic entity that is organized as a multilayer system and
includes various intracellular and extracellular elements. The gut barrier functions in a …
includes various intracellular and extracellular elements. The gut barrier functions in a …