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Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
Self-assembling prodrugs
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …
Nanoparticles and targeted drug delivery in cancer therapy
Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …
Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering
Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …
Brain penetrating peptides and peptide–drug conjugates to overcome the blood–brain barrier and target CNS diseases
Nearly one in six people worldwide suffer from disorders of the central nervous system
(CNS). There is an urgent need for effective strategies to improve the success rates in CNS …
(CNS). There is an urgent need for effective strategies to improve the success rates in CNS …
Applications of elastin-like polypeptides in drug delivery
Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …
critical solution temperature phase transition behavior and biocompatibility make them …
Stimuli-responsive copolymer solution and surface assemblies for biomedical applications
Stimuli-responsive polymeric materials is one of the fastest growing fields of the 21st
century, with the annual number of papers published more than quadrupling in the last ten …
century, with the annual number of papers published more than quadrupling in the last ten …
A smart hyperthermia nanofiber with switchable drug release for inducing cancer apoptosis
A smart hyperthermia nanofiber is described with simultaneous heat generation and drug
release in response to 'on‐off'switching of alternating magnetic field (AMF) for induction of …
release in response to 'on‐off'switching of alternating magnetic field (AMF) for induction of …
Advances in peptide-based drug delivery systems
S Guo, J Wang, Q Wang, J Wang, S Qin, W Li - Heliyon, 2024 - cell.com
Drug delivery systems (DDSs) are designed to deliver drugs to their specific targets to
minimize their toxic effects and improve their susceptibility to clearance during targeted …
minimize their toxic effects and improve their susceptibility to clearance during targeted …
A Unified Model for De Novo Design of Elastin-like Polypeptides with Tunable Inverse Transition Temperatures
Elastin-like polypeptides (ELPs) are stimulus-responsive peptide polymers that exhibit
inverse temperature phase transition behavior, causing an ELP to aggregate above its …
inverse temperature phase transition behavior, causing an ELP to aggregate above its …