Innate immunity: the first line of defense against SARS-CoV-2
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …
devastating consequences. While the medical community has gained insight into the …
[HTML][HTML] MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells
Recent studies have profiled the innate immune signatures in patients infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and suggest that cellular …
Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries
Abstract The chr12q24. 13 locus encoding OAS1–OAS3 antiviral proteins has been
associated with coronavirus disease 2019 (COVID-19) susceptibility. Here, we report …
associated with coronavirus disease 2019 (COVID-19) susceptibility. Here, we report …
Potential intestinal infection and faecal–oral transmission of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance
R Robinot, M Hubert, GD De Melo, F Lazarini… - Nature …, 2021 - nature.com
Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define
the parameters controlling the severity of COVID-19. Here we examine the functional and …
the parameters controlling the severity of COVID-19. Here we examine the functional and …
Human organoid models to study SARS-CoV-2 infection
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
AK Reuschl, LG Thorne, MVX Whelan… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health …
the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health …
A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …