Obesity is a chronic disease characterized by the abnormal or excessive accumulation of
body fat, affecting more than 1 billion people worldwide. Obesity is commonly associated …

Desmoplastic reaction is a fibrosis reaction that is characterized by a large amount of dense
extracellular matrix (ECM) and dense fibrous stroma. Fibrotic stroma around the tumor has …

MicroRNAs (miRNAs) are secreted from cells as either protein-bound or enclosed in
extracellular vesicles. Circulating liver-derived miRNAs are modifiable by weight-loss or …

Gestational diabetes mellitus (GDM) is a severe pregnancy complication for both the woman
and the child. Women who suffer from GDM have a greater risk of develo** Type 2 …

Bacteria that have worked with humans for thousands of years pose a major threat to human
health even today, as drug resistance has become a prominent problem. Compared to …

In this study, we conducted a systematic review and meta-analysis to summarize and
evaluate the global research potential of different circulating miRNAs as an early diagnostic …

Background Coexistent sarcopenia and frailty is more strongly associated with adverse
health outcomes than each condition alone. As the importance of coexistent sarcopenia and …

This study explores a novel therapeutic approach for peritoneal metastasis (PM) using AAV-
mediated delivery of tumor suppressor microRNA-29b (miR-29b) to peritoneal mesothelial …

The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides
protection against myocardial ischemia/reperfusion (I/R) injury in diabetes. Since …

Circulating plasma miRNAs have emerged as potential early predictors of glucometabolic
disorders. However, their biomarker potential remains unvalidated in populations with …