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Development of broad-spectrum nanobodies for the therapy and diagnosis of SARS-CoV-2 and its multiple variants
L He, Q Wu, Z Zhang, L Chen, K Yu, L Li… - Molecular …, 2024 - ACS Publications
The continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has evaded the efficacy of previously developed antibodies and vaccines, thus remaining …
2) has evaded the efficacy of previously developed antibodies and vaccines, thus remaining …
Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA. 5 sublineages
Y Li, S Qin, L Dong, Y **ao, Y Zhang, Y Hou, S Qiao… - …, 2024 - thelancet.com
Background Omicron sub-variants breakthrough infections (BTIs) have led to millions of
coronavirus disease 2019 (COVID-19) cases worldwide. The acute-phase immune status is …
coronavirus disease 2019 (COVID-19) cases worldwide. The acute-phase immune status is …
Robust mucosal SARS-CoV-2-specific T cells effectively combat COVID-19 and establish polyfunctional resident memory in patient lungs
A Zhu, Z Chen, Q Yan, M Jiang, X Liu, Z Li, N Li… - Nature …, 2025 - nature.com
Mucosal antigen-specific T cells are pivotal for pathogen clearance and immune modulation
in respiratory infections. Dysregulated T cell responses exacerbate coronavirus disease …
in respiratory infections. Dysregulated T cell responses exacerbate coronavirus disease …
Antibody dynamics for heterologous boosters with aerosolized Ad5-nCoV following inactivated COVID-19 vaccines
C Chen, T Tang, Z Chen, L Chen, J Cheng… - Human Vaccines & …, 2024 - Taylor & Francis
The COVID-19 pandemic has underscored vaccination as a crucial strategy for reducing
disease severity and preventing hospitalizations. Heterologous boosters using aerosolized …
disease severity and preventing hospitalizations. Heterologous boosters using aerosolized …