Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans

DHJ Thijssen, RM Bruno, ACCM van Mil… - European heart …, 2019 - academic.oup.com
Endothelial dysfunction is involved in the development of atherosclerosis, which precedes
asymptomatic structural vascular alterations as well as clinical manifestations of …

The assessment of endothelial function: from research into clinical practice

AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

[HTML][HTML] Endothelial cell infection and endotheliitis in COVID-19

Z Varga, AJ Flammer, P Steiger, M Haberecker… - The Lancet, 2020 - thelancet.com
Cardiovascular complications are rapidly emerging as a key threat in coronavirus disease
2019 (COVID-19) in addition to respiratory disease. The mechanisms underlying the …

[HTML][HTML] COVID-19: the case for health-care worker screening to prevent hospital transmission

JRM Black, C Bailey, J Przewrocka, KK Dijkstra… - The Lancet, 2020 - thelancet.com
COVID-19: the case for health-care worker screening to prevent hospital transmission - The
Lancet Skip to Main Content Advertisement The Lancet Journal Submit Article Log in Register …

Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions

P Raggi, J Genest, JT Giles, KJ Rayner, G Dwivedi… - Atherosclerosis, 2018 - Elsevier
Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

[HTML][HTML] The endothelium and its role in regulating vascular tone

A Sandoo, JJCSV van Zanten, GS Metsios… - The open …, 2010 - ncbi.nlm.nih.gov
The endothelium forms an important part of the vasculature and is involved in promoting an
atheroprotective environment via the complementary actions of endothelial cell-derived …

Inflammation and cardiovascular disease: from pathogenesis to therapeutic target

E Golia, G Limongelli, F Natale, F Fimiani… - Current atherosclerosis …, 2014 - Springer
Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …

Explaining how “high-grade” systemic inflammation accelerates vascular risk in rheumatoid arthritis

N Sattar, DW McCarey, H Capell, IB McInnes - Circulation, 2003 - Am Heart Assoc
There is intense interest in mechanisms whereby low-grade inflammation could interact with
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …

Endothelial dysfunction in chronic inflammatory diseases

CM Steyers III, FJ Miller Jr - International journal of molecular sciences, 2014 - mdpi.com
Chronic inflammatory diseases are associated with accelerated atherosclerosis and
increased risk of cardiovascular diseases (CVD). As the pathogenesis of atherosclerosis is …

Anti-inflammatory therapies for cardiovascular disease

PM Ridker, TF Lüscher - European heart journal, 2014 - academic.oup.com
Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …