Dysregulated lipid metabolism links NAFLD to cardiovascular disease

A Deprince, JT Haas, B Staels - Molecular metabolism, 2020 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming a global health
problem. Cardiovascular diseases (CVD) are the most common cause of mortality in NAFLD …

Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2019 - Elsevier
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures–2019 update: cosponsored …

JI Mechanick, C Apovian, S Brethauer… - Surgery for Obesity and …, 2020 - Elsevier
Objective The development of these updated clinical practice guidelines (CPG) was
commissioned by the American Association of Clinical Endocrinologists, The Obesity …

ESPEN guideline on clinical nutrition in liver disease

M Plauth, W Bernal, S Dasarathy, M Merli, LD Plank… - Clinical nutrition, 2019 - Elsevier
This update of evidence-based guidelines (GL) aims to translate current evidence and
expert opinion into recommendations for multidisciplinary teams responsible for the optimal …

Therapeutic pipeline in nonalcoholic steatohepatitis

R Vuppalanchi, M Noureddin, N Alkhouri… - Nature Reviews …, 2021 - nature.com
Our understanding of nonalcoholic fatty liver disease pathophysiology continues to advance
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …

NAFLD and diabetes mellitus

H Tilg, AR Moschen, M Roden - Nature reviews Gastroenterology & …, 2017 - nature.com
The liver constitutes a key organ in systemic metabolism, contributing substantially to the
development of insulin resistance and type 2 diabetes mellitus (T2DM). The mechanisms …

EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

European Association for the Study of the Liver (EASL) … - Obesity facts, 2016 - karger.com
The Clinical Practice Guidelines (CPG) propose recommendations for the diagnosis,
treatment and follow-up of non-alcoholic fatty liver disease (NAFLD) patients and are the …

Treatment of obesity: weight loss and bariatric surgery

BM Wolfe, E Kvach, RH Eckel - Circulation research, 2016 - ahajournals.org
This review focuses on the mechanisms underlying, and indications for, bariatric surgery in
the reduction of cardiovascular disease (CVD), as well as other expected benefits of this …

Complete resolution of nonalcoholic fatty liver disease after bariatric surgery: a systematic review and meta-analysis

Y Lee, AG Doumouras, J Yu, K Brar, L Banfield… - Clinical …, 2019 - Elsevier
Background & Aims Bariatric surgery has been reported to lead to complete resolution of
nonalcoholic fatty liver disease (NAFLD) following the sustained weight loss induced in …