Mycobacterium smegmatis: the vanguard of mycobacterial research
IL Sparks, KM Derbyshire, WR Jacobs Jr… - Journal of …, 2023 - Am Soc Microbiol
The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …
Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates
Mycobacteriophages show promise as therapeutic agents for non-tuberculous
mycobacterium infections. However, little is known about phage recognition of …
mycobacterium infections. However, little is known about phage recognition of …
Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection
MR Sullivan, K McGowen, Q Liu, C Akusobi… - Nature …, 2023 - nature.com
Mycobacterium abscessus is an emerging pathogen causing lung infection predominantly in
patients with underlying structural abnormalities or lung disease and is resistant to most …
patients with underlying structural abnormalities or lung disease and is resistant to most …
In vitro activity of cefoxitin, imipenem, meropenem, and ceftaroline in combination with vaborbactam against Mycobacterium abscessus
L Chen, E Shashkina, N Kurepina… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Mycobacterium abscessus (MAB) infections pose a growing public health threat. Here, we
assessed the in vitro activity of the boronic acid-based β-lactamase inhibitor, vaborbactam …
assessed the in vitro activity of the boronic acid-based β-lactamase inhibitor, vaborbactam …
Identification of drivers of mycobacterial resistance to peptidoglycan synthesis inhibitors
Beta-lactams have been excluded from tuberculosis therapy due to the intrinsic resistance of
Mycobacterium tuberculosis (Mtb) to this antibiotic class, usually attributed to a potent beta …
Mycobacterium tuberculosis (Mtb) to this antibiotic class, usually attributed to a potent beta …
Mycobacterium abscessus DosRS two-component system controls a species-specific regulon required for adaptation to hypoxia
Mycobacterium abscessus (Mab), an emerging opportunistic pathogen, predominantly
infects individuals with underlying pulmonary diseases such as cystic fibrosis (CF). Current …
infects individuals with underlying pulmonary diseases such as cystic fibrosis (CF). Current …
MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus
R Rodriguez, N Campbell-Kruger… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Mycobacterium abscessus (Mabs) is an emerging nontuberculosis mycobacterial (NTM)
pathogen responsible for a wide variety of respiratory and cutaneous infections that are …
pathogen responsible for a wide variety of respiratory and cutaneous infections that are …
Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZMab
R Gupta, KH Rohde - Tuberculosis, 2023 - Elsevier
Mycobacterium abscessus (Mab) is a highly drug-resistant non-tuberculous mycobacterial
species that causes debilitating TB-like pulmonary infections. The lack of genetic tools has …
species that causes debilitating TB-like pulmonary infections. The lack of genetic tools has …
Chemical approaches to unraveling the biology of mycobacteria
Mycobacterium tuberculosis (Mtb), perhaps more than any other organism, is intrinsically
appealing to chemical biologists. Not only does the cell envelope feature one of the most …
appealing to chemical biologists. Not only does the cell envelope feature one of the most …
Durlobactam in combination with β-lactams to combat Mycobacterium abscessus
Mycobacterium abscessus (Mab) presents significant clinical challenges. This study
evaluated the synergistic effects of a β-lactam and β-lactamase inhibitor combination against …
evaluated the synergistic effects of a β-lactam and β-lactamase inhibitor combination against …