The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

Gases like H2, N2, CO2, and CO are increasingly recognized as critical feedstock in “green”
energy conversion and as sources of nitrogen and carbon for the agricultural and chemical …

This article sets out to review the chemistry relating to the synthesis of structural and
functional analogues of the three classes of hydrogenases. This chemistry has grown …

The utilization of hydrogen by micro-organisms as a source of reducing power or of protons
as final electron acceptors is mediated by metalloenzymes called hydrogenases. The need …

Abstract The [FeFe]-and [NiFe]-hydrogenases catalyze the formal interconversion between
hydrogen and protons and electrons, possess characteristic non-protein ligands at their …

4366 Chem. Rev. 2007, 107, 4366− 4413 10.1021/cr050191u CCC: $65.00© 2007
American Chemical Society Published on Web 09/11/2007 the lower atmosphere1) because …

Over the last 15 years, a plethora of research has provided major insights into the structure
and function of hydrogenase enzymes. This has led to the important development of …

Biological formation and consumption of molecular hydrogen (H2) are catalyzed by
hydrogenases, of which three phylogenetically unrelated types are known:[NiFe] …

In biological systems, the amino acid cysteine combines catalytic activity with an extensive
redox chemistry and unique metal binding properties. The interdependency of these three …

Nickel is one of 23 metal pollutants of great concern to the environment and to human health
(Sunderman 1992; Jarup 2003; Duda-Chodak and Baszczyk 2008). Nickel is the 24th most …