Telomeres are highly conserved tandem nucleotide repeats that include proximal double-
stranded and distal single-stranded regions that in complex with shelterin proteins afford …

Telomere length (TL) is a dynamic marker that reflects genetic predispositions together with
the environmental conditions of an individual. It is closely related to longevity and a number …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Genome-wide association studies (GWAS) have identified thousands of germline
susceptibility loci associated with risk for cancer as well as a wide range of other traits and …

Genetic studies on telomere length are important for understanding age-related diseases.
Prior GWASs for leukocyte TL have been limited to European and Asian populations. Here …

Background Telomere length (TL) and its attrition are important indicators of physiological
stress and biological aging and hence may vary among individuals of the same age. This …

Uterine leiomyomas (ULs) are benign tumors that are a major burden to women's health. A
genome-wide association study on 15,453 UL cases and 392,628 controls was performed …

Background Telomere maintenance is increasingly recognized as being fundamental to
glioma oncogenesis with longer leukocyte telomere length (LTL) reported to increase risk of …

In the last decades the association of leukocyte telomere length (LTL) and mitochondrial
copy number (mtDNAcn) with cancer risk has been the focus of many reports, however the …

Purpose: EGF receptor (EGFR) mutation–positive (EGFRmut+) non–small cell lung cancer
(NSCLC) may be a unique orphan disease. Previous studies suggested that the telomerase …