Target-triggered multiple-polarity-switchable multiplexed photoelectrochemical platform
ZL Ma, JJ Chen, XF Sun, Y **e, H Luo… - Analytical …, 2024 - ACS Publications
Convenient and accurate quantification of disease-relevant multitargets is essential for
community disease screening. However, in the field of photoelectrochemical (PEC) sensors …
community disease screening. However, in the field of photoelectrochemical (PEC) sensors …
Revolutionizing Alzheimer's Treatment: Harnessing Human Serum Albumin for Targeted Drug Delivery and Therapy Advancements
Alzheimer's disease (AD) is a neurodegenerative disorder initiated by amyloid-beta (Aβ)
accumulation, leading to impaired cognitive function. Several delivery approaches have …
accumulation, leading to impaired cognitive function. Several delivery approaches have …
Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies
S Liu, H Li, S **, Y Zhang, T Sun - International Journal of …, 2025 - Taylor & Francis
Given the complexity of the central nervous system (CNS) and the diversity of neurological
conditions, the increasing prevalence of neurological disorders poses a significant …
conditions, the increasing prevalence of neurological disorders poses a significant …
Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro
S Digiovanni, M Lorenzati, OT Bianciotto… - Fluids and Barriers of …, 2024 - Springer
Background Glioblastoma multiforme (GBM) is an aggressive tumor, difficult to treat
pharmacologically because of the blood-brain barrier (BBB), which is rich in ATP-binding …
pharmacologically because of the blood-brain barrier (BBB), which is rich in ATP-binding …
Nanoparticles crossing blood–brain barrier need specific design for normal, neurodegenerative or cancerous brain conditions
Central nervous system (CNS) diseases including depression, stroke, brain infection, brain
cancer, neurodegenerations, meningitis, neuropathic pain, amyotrophic lateral sclerosis …
cancer, neurodegenerations, meningitis, neuropathic pain, amyotrophic lateral sclerosis …
MiR-25802: a potential target for treating Alzheimer's disease by regulating neuroinflammation
K Zhao, Z Li, L Zeng, Z Cai, R Liu - Frontiers in Immunology, 2024 - frontiersin.org
Alzheimer's disease (AD) holds global significance as a neurodegenerative disorder with a
complex etiology still partly understood. Recent advancements in genetic and molecular …
complex etiology still partly understood. Recent advancements in genetic and molecular …
[HTML][HTML] Nano-Polymers as Cas9 Inhibitors
O Chepurna, A Chatterjee, Y Li, H Ding, R Murali… - Polymers, 2025 - mdpi.com
Despite wide applications of CRISPR/Cas9 technology, effective approaches for CRISPR
delivery with functional control are limited. In an attempt to develop a nanoscale …
delivery with functional control are limited. In an attempt to develop a nanoscale …
The LDL Receptor-Related Protein 1: Mechanisms and roles in promoting Aβ efflux transporter in Alzheimer's disease
W Li, C Chen, B Xu, J Chen, M Yang, L Gao… - Biochemical …, 2024 - Elsevier
Abstract The LDL Receptor-Related Protein 1 (LRP1), a member of the Low-density
Lipoprotein (LDL) receptor family, is a multifunctional cellular transporter and signaling …
Lipoprotein (LDL) receptor family, is a multifunctional cellular transporter and signaling …
Nanoscale drug formulations for the treatment of Alzheimer's disease progression
L Liu, H He, B Du, Y He - RSC Advances, 2025 - pubs.rsc.org
Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no effective
disease-modifying treatments. The blood–brain barrier hinders drug delivery to the brain …
disease-modifying treatments. The blood–brain barrier hinders drug delivery to the brain …
Serum miRNA Detection-based Alzheimer's disease prediction regression model
S Liu, Y Li, Y Zhang, Y Guo, J Zhang - Molecular & Cellular …, 2024 - sin-chn.com
With the deepening of Alzheimer's disease (AD) research, serum miRNA has attracted
widespread attention as a potential biomarker. Traditional diagnostic methods for AD have …
widespread attention as a potential biomarker. Traditional diagnostic methods for AD have …