Target-triggered multiple-polarity-switchable multiplexed photoelectrochemical platform

ZL Ma, JJ Chen, XF Sun, Y **e, H Luo… - Analytical …, 2024 - ACS Publications
Convenient and accurate quantification of disease-relevant multitargets is essential for
community disease screening. However, in the field of photoelectrochemical (PEC) sensors …

Revolutionizing Alzheimer's Treatment: Harnessing Human Serum Albumin for Targeted Drug Delivery and Therapy Advancements

D Shastri, V Raj, S Lee - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder initiated by amyloid-beta (Aβ)
accumulation, leading to impaired cognitive function. Several delivery approaches have …

Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies

S Liu, H Li, S **, Y Zhang, T Sun - International Journal of …, 2025 - Taylor & Francis
Given the complexity of the central nervous system (CNS) and the diversity of neurological
conditions, the increasing prevalence of neurological disorders poses a significant …

Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

S Digiovanni, M Lorenzati, OT Bianciotto… - Fluids and Barriers of …, 2024 - Springer
Background Glioblastoma multiforme (GBM) is an aggressive tumor, difficult to treat
pharmacologically because of the blood-brain barrier (BBB), which is rich in ATP-binding …

Nanoparticles crossing blood–brain barrier need specific design for normal, neurodegenerative or cancerous brain conditions

JY Ljubimova, E Holler, KL Black, AV Ljubimov - Nanomedicine, 2024 - Taylor & Francis
Central nervous system (CNS) diseases including depression, stroke, brain infection, brain
cancer, neurodegenerations, meningitis, neuropathic pain, amyotrophic lateral sclerosis …

MiR-25802: a potential target for treating Alzheimer's disease by regulating neuroinflammation

K Zhao, Z Li, L Zeng, Z Cai, R Liu - Frontiers in Immunology, 2024 - frontiersin.org
Alzheimer's disease (AD) holds global significance as a neurodegenerative disorder with a
complex etiology still partly understood. Recent advancements in genetic and molecular …

[HTML][HTML] Nano-Polymers as Cas9 Inhibitors

O Chepurna, A Chatterjee, Y Li, H Ding, R Murali… - Polymers, 2025 - mdpi.com
Despite wide applications of CRISPR/Cas9 technology, effective approaches for CRISPR
delivery with functional control are limited. In an attempt to develop a nanoscale …

The LDL Receptor-Related Protein 1: Mechanisms and roles in promoting Aβ efflux transporter in Alzheimer's disease

W Li, C Chen, B Xu, J Chen, M Yang, L Gao… - Biochemical …, 2024 - Elsevier
Abstract The LDL Receptor-Related Protein 1 (LRP1), a member of the Low-density
Lipoprotein (LDL) receptor family, is a multifunctional cellular transporter and signaling …

Nanoscale drug formulations for the treatment of Alzheimer's disease progression

L Liu, H He, B Du, Y He - RSC Advances, 2025 - pubs.rsc.org
Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no effective
disease-modifying treatments. The blood–brain barrier hinders drug delivery to the brain …

Serum miRNA Detection-based Alzheimer's disease prediction regression model

S Liu, Y Li, Y Zhang, Y Guo, J Zhang - Molecular & Cellular …, 2024 - sin-chn.com
With the deepening of Alzheimer's disease (AD) research, serum miRNA has attracted
widespread attention as a potential biomarker. Traditional diagnostic methods for AD have …