NMR investigation of RNA structure

G Varani, F Aboul-Ela, FHT Allain - Progress in Nuclear Magnetic …, 1996 - Elsevier
The many important biological functions of RNA range from propagation of genetic
information to catalysis in RNA processing and protein synthesis [l]. This diverse array of …

RNA structure and NMR spectroscopy

G Varani, I Tinoco Jr - Quarterly reviews of biophysics, 1991 - cambridge.org
RNA structure and NMR spectroscopy Page 1 Quarterly Reviews of Biophysics 24, 4 (1991), pp.
479-532 4 7 9 Printed in Great Britain RNA structure and NMR spectroscopy GABRIELE …

[16] Studies of base pair kinetics by NMR measurement of proton exchange

M Guéron, JL Leroy - Methods in enzymology, 1995 - Elsevier
Publisher Summary This chapter discusses the studies of base pair kinetics by nuclear
magnetic resonance (NMR) measurement of proton exchange. Base pairing is ubiquitous in …

Structure of the P1 helix from group I self-splicing introns

FHT Allain, G Varani - Journal of molecular biology, 1995 - Elsevier
The upstream cleavage site of group I self-splicing introns is identified by an absolutely
conserved U· G base-pair within a double helix. Mutant introns with a wobble C· A substitute …

Classification and energetics of the base-phosphate interactions in RNA

CL Zirbel, JE Šponer, J Šponer… - Nucleic acids …, 2009 - academic.oup.com
Structured RNA molecules form complex 3D architectures stabilized by multiple interactions
involving the nucleotide base, sugar and phosphate moieties. A significant percentage of the …

RNA dynamics by NMR spectroscopy

M Marušič, J Schlagnitweit, K Petzold - ChemBioChem, 2019 - Wiley Online Library
An ever‐increasing number of functional RNAs require a mechanistic understanding. RNA
function relies on changes in its structure, so‐called dynamics. To reveal dynamic processes …

Characterization of base-pair opening in deoxynucleotide duplexes using catalyzed exchange of the imino proton

JL Leroy, M Kochoyan, T Huynh-Dinh… - Journal of molecular …, 1988 - Elsevier
Using nuclear magnetic resonance line broadening, longitudinal relaxation and
magnetization transfer from water, we have measured the imino proton exchange times in …

Characterizing micro-to-millisecond chemical exchange in nucleic acids using off-resonance R1ρ relaxation dispersion

A Rangadurai, ES Szymaski, IJ Kimsey, H Shi… - Progress in nuclear …, 2019 - Elsevier
This review describes off-resonance R 1ρ relaxation dispersion NMR methods for
characterizing microsecond-to-millisecond chemical exchange in uniformly 13 C/15 N …

Evidence from base-pair kinetics for two types of adenine tract structures in solution: their relation to DNA curvature

JL Leroy, E Charretier, M Kochoyan, M Gueron - Biochemistry, 1988 - ACS Publications
Methods The methods for assigning spectra and measuring base-pair lifetimes in
oligoduplexeshave been described (Leroy et al., 1988). The imino proton NMR spectrum of …

Rules governing the orientation of the 2′-hydroxyl group in RNA

P Auffinger, E Westhof - Journal of molecular biology, 1997 - Elsevier
Molecular dynamics simulations reveal that, in C3′-endo sugar puckers, only three
orientations are accessible to the 2′-hydroxyl groups distinctive of RNA molecules: towards …