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Genetics factors in major depression disease
M Shadrina, EA Bondarenko, PA Slominsky - Frontiers in psychiatry, 2018 - frontiersin.org
Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …
According to the World Health Organization, about 350 million people in the world are …
Prenatal stress, maternal immune dysregulation, and their association with autism spectrum disorders
Abstract Purpose of Review While genetic factors are a major etiological contributor to
autism spectrum disorder (ASD), evidence also supports a role for environmental factors …
autism spectrum disorder (ASD), evidence also supports a role for environmental factors …
A systematic review of genetic influence on psychological resilience
When exposed to adversity, some individuals are at an increased risk of posttraumatic stress
disorder, experiencing persistent biopsychosocial disturbances, whereas others adapt well …
disorder, experiencing persistent biopsychosocial disturbances, whereas others adapt well …
Role of the 5-HTTLPR and SNP promoter polymorphisms on serotonin transporter gene expression: a closer look at genetic architecture and in vitro functional studies …
Abstract The serotonin (5-hydroxytriptamine (5-HT)) transporter (5-HTT) gene-linked
polymorphic region (5-HTTLPR) is a variable number tandem repeats (VNTR) located in the …
polymorphic region (5-HTTLPR) is a variable number tandem repeats (VNTR) located in the …
Precision medicine: does ethnicity information complement genotype-based prescribing decisions?
RR Shah, A Gaedigk - Therapeutic advances in drug safety, 2018 - journals.sagepub.com
Inter-ethnic differences in drug response are all too well known. These are underpinned by a
number of factors, including pharmacogenetic differences across various ethnic populations …
number of factors, including pharmacogenetic differences across various ethnic populations …
An integrative review of methylation at the serotonin transporter gene and its dialogue with environmental risk factors, psychopathology and 5-HTTLPR
H Palma-Gudiel, L Fañanás - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Abstract Gene—environment (G× E) interactions have largely been regarded as the root of
many complex disorders, including several psychiatric disorders. In this regard, it has been …
many complex disorders, including several psychiatric disorders. In this regard, it has been …
The role of serotonin in depression—A historical roundup and future directions
S Bremshey, J Groß, K Renken… - Journal of …, 2024 - Wiley Online Library
Depression is one of the most common psychiatric disorders worldwide, affecting
approximately 280 million people, with probably much higher unrecorded cases …
approximately 280 million people, with probably much higher unrecorded cases …
Maternal serotonin transporter genotype affects risk for ASD with exposure to prenatal stress
PM Hecht, M Hudson, SL Connors, MR Tilley… - Autism …, 2016 - Wiley Online Library
Stress exposure during gestation is implicated in several neuropsychiatric conditions,
including autism spectrum disorder (ASD). Previous research showed that prenatal stress …
including autism spectrum disorder (ASD). Previous research showed that prenatal stress …
Gender-specific association between serotonin transporter polymorphisms (5-HTTLPR and rs25531) and neuroticism, anxiety and depression in well-defined healthy …
CC Chang, HA Chang, WH Fang, TC Chang… - Journal of Affective …, 2017 - Elsevier
Background A tri-allelic serotonin transporter promoter polymorphism (5-HTTLPR/rs25531)
more effectively determines the levels of transcriptional efficacy than that with the bi-allelic 5 …
more effectively determines the levels of transcriptional efficacy than that with the bi-allelic 5 …
Perinatal vs genetic programming of serotonin states associated with anxiety
SC Altieri, H Yang, HJ O'brien, HM Redwine… - …, 2015 - nature.com
Large numbers of women undergo antidepressant treatment during pregnancy; however,
long-term consequences for their offspring remain largely unknown. Rodents exposed to …
long-term consequences for their offspring remain largely unknown. Rodents exposed to …