Neurodegenerative disorders (NDs) have become increasingly common during the past
three decades. Approximately 15% of the total population of the world is affected by some …

Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds
developed to probe the endogenous cannabinoid system or as potential therapeutics …

Most neurodegenerative disorders (NDD s) are characterized by cognitive impairment and
other neurological defects. The definite cause of and pathways underlying the progression …

Cannabinoid-derived drugs are promising agents for the development of novel
neuroprotective strategies. Activation of neuronal CB1 cannabinoid receptors attenuates …

Cannabis sativa L. preparations have been used in medicine for millenia. However, concern
over the dangers of abuse led to the banning of the medicinal use of marijuana in most …

Different plant-derived and synthetic cannabinoids have shown to be neuroprotective in
experimental models of Huntington's disease (HD) through cannabinoid receptor-dependent …

Cannabinoids form a singular family of plant-derived compounds (phytocannabinoids),
endogenous signaling lipids (endocannabinoids), and synthetic derivatives with multiple …

The endocannabinoid system (ECS) exerts a modulatory effect of important functions such
as neurotransmission, glial activation, oxidative stress, or protein homeostasis …

This review focuses on the role of the endocannabinoid signaling system in controlling
neuronal survival, an extremely important issue to be considered when develo** new …

Endocannabinoids act as neuromodulatory and neuroprotective cues by engaging type 1
cannabinoid receptors. These receptors are highly abundant in the basal ganglia and play a …