Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Nemaline myopathies are a heterogenous group of congenital myopathies caused by de
novo, dominantly or recessively inherited mutations in at least twelve genes. The genes …

The nemaline myopathies constitute a large proportion of the congenital or structural
myopathies. Common to all patients is muscle weakness and the presence in the muscle …

Background Cannabis legalization is expanding and men are the predominant users. We
have limited knowledge about how cannabis impacts sperm and whether the effects are …

Maintenance of skeletal muscle quantity and quality is essential to ensure various vital
functions of the body. Muscle homeostasis is regulated by multiple cytoskeletal proteins and …

Development is a complex process that occurs throughout the life cycle. F-actin, a major
component of the cytoskeleton, is essential for the morphogenesis of tissues and organs …

The actin containing tropomyosin and troponin decorated thin filaments form one of the
crucial components of the contractile apparatus in muscles. The thin filaments are organized …

The underlying mechanisms for statin-induced myopathy (SIM) are still equivocal. In this
study, we employ Drosophila melanogaster to dissect possible underlying mechanisms for …

Cyclase-associated protein (CAP) is an actin binding protein that has been initially
described as partner of the adenylyl cyclase in yeast. In all vertebrates and some …

Nemaline myopathy (NM) is a genetically and clinically heterogeneous disease that is
diagnosed on the basis of the presence of nemaline rods on skeletal muscle biopsy …