Using support vector machine to identify imaging biomarkers of neurological and psychiatric disease: a critical review

G Orru, W Pettersson-Yeo, AF Marquand… - Neuroscience & …, 2012 - Elsevier
Standard univariate analysis of neuroimaging data has revealed a host of neuroanatomical
and functional differences between healthy individuals and patients suffering a wide range …

Huntington disease: natural history, biomarkers and prospects for therapeutics

CA Ross, EH Aylward, EJ Wild, DR Langbehn… - Nature Reviews …, 2014 - nature.com
Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is
caused by a single genetic mutation and is amenable to predictive genetic testing, with …

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data

SJ Tabrizi, DR Langbehn, BR Leavitt… - The Lancet …, 2009 - thelancet.com
Background Huntington's disease (HD) is an autosomal dominant, fully penetrant,
neurodegenerative disease that most commonly affects adults in mid-life. Our aim was to …

Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis

SJ Tabrizi, RI Scahill, A Durr, RAC Roos… - The Lancet …, 2011 - thelancet.com
Background TRACK-HD is a prospective observational study of Huntington's disease (HD)
that examines disease progression in premanifest individuals carrying the mutant HTT gene …

Evidence for segregated and integrative connectivity patterns in the human basal ganglia

B Draganski, F Kherif, S Klöppel, PA Cook… - Journal of …, 2008 - Soc Neuroscience
Detailed knowledge of the anatomy and connectivity pattern of cortico-basal ganglia circuits
is essential to an understanding of abnormal cortical function and pathophysiology …

Unraveling the complexity of human brain: Structure, function in healthy and disease states

OF Sultana, M Bandaru, MA Islam, PH Reddy - Ageing Research Reviews, 2024 - Elsevier
The human brain stands as an intricate organ, embodying a nexus of structure, function,
development, and diversity. This review delves into the multifaceted landscape of the brain …

Diffusion imaging, white matter, and psychopathology

ME Thomason, PM Thompson - Annual review of clinical …, 2011 - annualreviews.org
The functional significance of the brain's white matter was not fully appreciated until new
imaging methods were developed to visualize fiber pathways and connections in the living …

[KNIHA][B] Vigor: Neuroeconomics of movement control

R Shadmehr, AA Ahmed - 2020 - books.google.com
An examination of the link between the vigor with which we move and the value that the
brain assigns to the goal of the movement. Why do we reflexively run toward people we love …

Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical “disconnection”

HD Rosas, SY Lee, AC Bender, AK Zaleta, M Vangel… - Neuroimage, 2010 - Elsevier
The corpus callosum (CC) is the major conduit for information transfer between the cerebral
hemispheres and plays an integral role in relaying sensory, motor and cognitive information …

[HTML][HTML] The contribution of glial cells to Huntington's disease pathogenesis

DK Wilton, B Stevens - Neurobiology of disease, 2020 - Elsevier
Glial cells play critical roles in the normal development and function of neural circuits, but in
many neurodegenerative diseases, they become dysregulated and may contribute to the …