Engineering bone/cartilage organoids: strategy, progress, and application

L Bai, D Zhou, G Li, J Liu, X Chen, J Su - Bone Research, 2024 - nature.com
The concept and development of bone/cartilage organoids are rapidly gaining momentum,
providing opportunities for both fundamental and translational research in bone biology …

Osteocytes and weightlessness

D Iandolo, M Strigini, A Guignandon, L Vico - Current osteoporosis reports, 2021 - Springer
Abstract Purpose of Review Osteocytes are considered to be the cells responsible for
mastering the remodeling process that follows the exposure to unloading conditions. Given …

Hydroxyapatite nanoparticles promote the development of bone microtissues for accelerated bone regeneration by activating the FAK/Akt pathway

L Li, H Li, Q Wang, Y Xue, Y Dai, Y Dong… - ACS Biomaterials …, 2024 - ACS Publications
Scaffold-free bone microtissues differentiated from mesenchymal stem cell (MSC) spheroids
offer great potential for bottom-up bone tissue engineering as a direct supply of cells and …

Modelling skeletal pain harnessing tissue engineering

L Iafrate, MC Benedetti, S Donsante, A Rosa, A Corsi… - In vitro models, 2022 - Springer
Bone pain typically occurs immediately following skeletal damage with mechanical distortion
or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain …

Scaffold-based bone tissue engineering in microgravity: potential, concerns and implications

F Mochi, E Scatena, D Rodriguez, MP Ginebra… - NPJ …, 2022 - nature.com
One of humanity's greatest challenges is space exploration, which requires an in-depth
analysis of the data continuously collected as a necessary input to fill technological gaps …

The management, treatment and study of skeletal pain harnessing tissue engineering models

L Iafrate, MC Benedetti, S Donsante, A Rosa… - arxiv preprint arxiv …, 2022 - arxiv.org
Bone pain typically occurs immediately following skeletal damage with mechanical distortion
or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain …