Frailty: implications for clinical practice and public health

EO Hoogendijk, J Afilalo, KE Ensrud, P Kowal, G Onder… - The Lancet, 2019 - thelancet.com
Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

Calcific aortic stenosis

BR Lindman, MA Clavel, P Mathieu, B Iung… - Nature reviews Disease …, 2016 - nature.com
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …

Frailty in older adults undergoing aortic valve replacement: the FRAILTY-AVR study

J Afilalo, S Lauck, DH Kim, T Lefèvre, N Piazza… - Journal of the American …, 2017 - jacc.org
Background Frailty is a geriatric syndrome that diminishes the potential for functional
recovery after a transcatheter aortic valve replacement (TAVR) or surgical aortic valve …

2017 ACC expert consensus decision pathway for transcatheter aortic valve replacement in the management of adults with aortic stenosis: a report of the American …

CM Otto, DJ Kumbhani, KP Alexander… - Journal of the American …, 2017 - jacc.org
The American College of Cardiology (ACC) develops a number of clinical policy documents
to provide members with guidance on clinical topics. Although clinical practice guidelines …

Management of acute coronary syndrome in the older adult population: a scientific statement from the American Heart Association

AA Damluji, DE Forman, TY Wang, J Chikwe… - Circulation, 2023 - Am Heart Assoc
Diagnostic and therapeutic advances during the past decades have substantially improved
health outcomes for patients with acute coronary syndrome. Both age-related physiological …

Relation of frailty to outcomes after transcatheter aortic valve replacement (from the PARTNER trial)

P Green, SV Arnold, DJ Cohen, AJ Kirtane… - The American journal of …, 2015 - Elsevier
Transcatheter aortic valve replacement (TAVR) is an effective treatment for severe
symptomatic aortic stenosis (AS) in patients who are inoperable or at high risk for surgery …

Cardiac imaging for assessing low-gradient severe aortic stenosis

MA Clavel, IG Burwash, P Pibarot - JACC: Cardiovascular Imaging, 2017 - jacc.org
Up to 40% of patients with aortic stenosis (AS) harbor discordant Doppler-
echocardiographic findings, the most common of which is the presence of a small aortic …

Antithrombotic therapy in atrial fibrillation associated with valvular heart disease: A joint consensus document from the European heart rhythm association (EHRA) and …

GYH Lip, JP Collet, R Caterina, L Fauchier… - Ep …, 2017 - academic.oup.com
Atrial fibrillation (AF) is a major worldwide public health problem, and AF in association with
valvular heart disease (VHD) is also common. However, management strategies for this …

2018 AATS/ACC/SCAI/STS expert consensus systems of care document: operator and institutional recommendations and requirements for transcatheter aortic valve …

JE Bavaria, CL Tommaso, RG Brindis, JD Carroll… - Journal of the American …, 2019 - jacc.org
Registry data that shows a clinically meaningful association of higher mortality and other
major complications with site annual volume below the recommended threshold of 50 …

The prevalence and prognostic significance of frailty in patients with advanced heart failure referred for heart transplantation

SR Jha, MK Hannu, S Chang, E Montgomery… - …, 2016 - journals.lww.com
Background Frailty is a clinically recognized syndrome of decreased physiological reserve.
The heightened state of vulnerability in these patients confers a greater risk of adverse …