[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning

JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Clinical trials of stem cell therapy for cerebral ischemic stroke

M Kawabori, H Shichinohe, S Kuroda… - International Journal of …, 2020 - mdpi.com
Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …

Cell death mechanisms in stroke and novel molecular and cellular treatment options

E Sekerdag, I Solaroglu… - Current …, 2018 - ingentaconnect.com
As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …

A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods

M Madrigal, KS Rao, NH Riordan - Journal of translational medicine, 2014 - Springer
The mesenchymal stem cell (MSC) is being broadly studied in clinical trials. Contrary to the
early paradigm of cell replacement and differentiation as a therapeutic mechanism of action …

Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

S Dabrowska, A Andrzejewska, B Lukomska… - Journal of …, 2019 - Springer
Ischemic stroke is the third cause of death in the developed countries and the main reason
of severe disability. Brain ischemia leads to the production of damage-associated molecular …

Biological applications of magnetic nanoparticles

M Colombo, S Carregal-Romero, MF Casula… - Chemical Society …, 2012 - pubs.rsc.org
In this review an overview about biological applications of magnetic colloidal nanoparticles
will be given, which comprises their synthesis, characterization, and in vitro and in vivo …

The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke

CJ Cunningham, E Redondo-Castro… - Journal of Cerebral …, 2018 - journals.sagepub.com
Mesenchymal stem cells (MSCs) hold great potential as a regenerative therapy for stroke,
leading to increased repair and functional recovery in animal models of cerebral ischaemia …