Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

Normal wound healing progresses through inflammatory, proliferative and remodeling
phases in response to tissue injury. Collagen, a key component of the extracellular matrix …

Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that∼ 8.2
million people had wounds with or without infections. Medicare cost estimates for acute and …

Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

The structure of connective tissues including cartilage, tendons, and ligaments as well as
many organs, like the skin, heart, liver, kidney, lungs, blood vessels, and bones, depend on …

Biofilm infection has a high prevalence in chronic wounds and can delay wound healing.
Current treatment using debridement and antibiotic administration imposes a significant …

Burn wounds can create significant damage to human skin, compromising one of the key
barriers to infection. The leading cause of death among burn wound patients is infection …

Bacterial infection often leads to inflammatory responses and delays wound healing.
Chitosan (CS)-based composite hydrogels can hold desirable mechanical properties and …

The healing of biofilm‐infected diabetic wounds characterized by a deteriorative tissue
microenvironment represents a substantial clinical challenge. Current treatments remain …

Collagen‐based hydrogels have a significant impact on wound healing, but they suffer from
structural instability and bacterial invasion in infected wounds. Here, electrospun nanofibers …